ArticleSexually transmitted infections2007
Prenatal syphilis infection is a possible cause of preterm delivery among immigrant women from eastern Europe.
Article in Sexually transmitted infections, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Incidence and associated factors of congenital syphilis at a tertiary care center in Thailand.Asian biomedicine : research, reviews and news · 2023Article
- Risk Factors Associated with Congenital Syphilis, Georgia, 2008-2015.Infectious diseases in obstetrics and gynecology · 2023Observational
- Syphilis-attributable adverse pregnancy outcomes in China: a retrospective cohort analysis of 1187 pregnant women with different syphilis treatment.BMC infectious diseases · 2019Article
- Contribution of a Comparative Western Blot Method to Early Postnatal Diagnosis of Congenital Syphilis.Clinical and vaccine immunology : CVI · 2016Article
- Evaluation of the BioPlex 2200 syphilis system as a first-line method of reverse-sequence screening for syphilis diagnosis.Clinical and vaccine immunology : CVI · 2013Article
- Syphilis Infection during pregnancy: fetal risks and clinical management.Infectious diseases in obstetrics and gynecology · 2012Article
- Congenital syphilis like many years ago.Case reports in infectious diseases · 2011Article
- Laboratory diagnosis of syphilis with automated immunoassays.Journal of clinical laboratory analysis · 2009Article
- Congenital syphilis in Italy.Sexually transmitted infections · 2007Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveto evaluate the prevalence of maternal syphilis at delivery and neonatal syphilis infection in an Italian urban area, in connection with the increased flow of immigration. STUDY
designA prospective surveillance study was carried out in Bologna, Italy, from November 2000 to March 2006. All pregnant women were screened for syphilis at delivery. Infants born to seropositive mothers were enrolled in a prospective follow-up.
resultsDuring the study period 19,205 women gave birth to 19,548 infants. A total of 85 women were seropositive for syphilis at delivery. The overall syphilis seroprevalence in pregnant women was 0.44%, but it was 4.3% in women from eastern Europe and 5.8% in women from Central-South America. Ten women were first found positive at delivery, as they did not receive any prenatal care. Nine of these were from eastern Europe. All their infants were asymptomatic, but six had both reactive immunoglobulin (Ig)M western blot and rapid plasma reagin tests and were considered prenatally infected. Three of six were preterm (gestational age <37 weeks).
conclusionsIn Italy, congenital syphilis infection is strictly related to immigration from eastern Europe. Although it is asymptomatic, it could cause premature delivery. Therefore, it is necessary to perform serological tests during the third trimester in mothers coming from endemic areas to adequately treat syphilis in pregnancy and prevent congenital infection. If the mother's test results are not available at delivery, it is necessary to investigate the newborn, especially if it is born prematurely.
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