Evidence map›Paper›PMID 17095552›Full record

SynthesisOccupational and environmental medicine2007

Risk of prematurity, low birthweight and pre-eclampsia in relation to working hours and physical activities: a systematic review.

Matteo Bonzini, David Coggon, Keith T Palmer

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Occupational and environmental medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 21 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 21 syntheses or guidelines pooled it.

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  14. Reproductive disorders among cosmetologists and hairdressers: a meta-analysis.International archives of occupational and environmental health · 2016
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  16. Physically demanding work and preterm delivery: a systematic review and meta-analysis.International archives of occupational and environmental health · 2014
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  17. Shift work, long working hours and preterm birth: a systematic review and meta-analysis.International archives of occupational and environmental health · 2014
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  20. Pregnancy: occupational aspects of management: concise guidance.Clinical medicine (London, England) · 2013
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matteo BonziniDepartment of Occupational Health, University of Milan, Foundation IRCCS Ospedale Maggiore, Milan, Italy.
David Coggon
Keith T Palmer

Funding

Medical Research Council MC_U147585823
6 · The paper itself

Abstract

backgroundOccupational activities are suspected of having an adverse impact on outcomes of pregnancy.

aimTo assess the evidence relating three major adverse outcomes (preterm delivery, low birthweight (LBW) and pre-eclampsia/gestational hypertension) to five common occupational exposures (prolonged working hours, shift work, lifting, standing and heavy physical workload).

methodsA systematic search of Medline and Embase (1966-December 2005) using combinations of keywords and medical subject heading terms was conducted. For each relevant paper, standard details were abstracted that were then used to summarise the design features of studies, to rate their methodological quality (completeness of reporting and potential for important bias or confounding) and to provide estimates of effect. For studies with similar definitions of exposure and outcome, pooled estimates of relative risk (RR) in meta-analysis were calculated.

results53 reports were identified-35 on preterm delivery, 34 on birth weight and 9 on pre-eclampsia or gestational hypertension. These included 21 cohort investigations. For pre-term delivery, extensive evidence relating to each of the exposures of interest was found. Findings were generally consistent and tended to rule out a more than moderate effect size (RR >1.4). The larger and most complete studies were less positive, and pooled estimates of risk pointed to only modest or null effects. For small-for-gestational age, the position was similar, but the evidence base was more limited. For pre-eclampsia and gestational hypertension, it was too small to allow firm conclusions.

conclusionsThe balance of evidence is not sufficiently compelling to justify mandatory restrictions on any of the activities considered in this review. However, given some uncertainties in the evidence base and the apparent absence of important beneficial effects, it may be prudent to advise against long working hours, prolonged standing and heavy physical work, particularly late in pregnancy. Our review identifies several priorities for future investigation.

Indexed as

Infant, Low Birth WeightExerciseFemaleHumansInfant, NewbornObstetric Labor, PrematureOccupational DiseasesPosturePre-EclampsiaPregnancyRisk FactorsWorkloadWork Schedule Tolerance

Identifiers

PMID17095552
PMCPMC2078455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.