ArticlePacific Symposium on Biocomputing. Pacific Symposium on Biocomputing2006
Discovering regulated networks during HIV-1 latency and reactivation.
Article in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions.PLoS neglected tropical diseases · 2016Article
- NDEx, the Network Data Exchange.Cell systems · 2015Article
- Integrative approaches for finding modular structure in biological networks.Nature reviews. Genetics · 2013Review
- High levels of CD2 expression identify HIV-1 latently infected resting memory CD4+ T cells in virally suppressed subjects.Journal of virology · 2013Article
- Shared molecular strategies of the malaria parasite P. falciparum and the human virus HIV-1.Molecular & cellular proteomics : MCP · 2011Article
- A new methodology to associate SNPs with human diseases according to their pathway related context.PloS one · 2011Article
- Computational prediction of host-parasite protein interactions between P. falciparum and H. sapiens.PloS one · 2011Article
- Article
- Viral organization of human proteins.PloS one · 2010Article
- Patterns of HIV-1 protein interaction identify perturbed host-cellular subsystems.PLoS computational biology · 2010Article
- Interpreting metabolomic profiles using unbiased pathway models.PLoS computational biology · 2010Article
- Cataloguing the HIV type 1 human protein interaction network.AIDS research and human retroviruses · 2008Review
- Systems biology and the host response to viral infection.Nature biotechnology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Human immunodeficiency virus (HIV) affects millions of people across the globe. Despite the introduction of powerful anti-viral therapies, one factor confounding viral elimination is the ability of HIV to remain latent within the host genome. Here, we perform a network analysis of the viral reactivation process using human gene expression profiles and curated databases of both human-human and human-HIV protein interactions. Based on this analysis, we report the identification of active pathways in both the latent and early phases of reactivation. These active pathways suggest host functions that are altered and important for HIV pathogenesis.
Indexed as
Identifiers
17094252PMC5224933W2088456856What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.