Trial reportApplied psychophysiology and biofeedback2006
Cardiovascular correlates of motor vehicle accident related posttraumatic stress disorder and its successful treatment.
Trial report in Applied psychophysiology and biofeedback, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Post-Traumatic Stress Disorder (PTSD) Resulting from Road Traffic Accidents (RTA): A Systematic Literature Review.International journal of environmental research and public health · 2025Pooled it
- Posttraumatic Stress Disorder Treatment Effects on Cardiovascular Physiology: A Systematic Review and Agenda for Future Research.Journal of traumatic stress · 2021Pooled it
- Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy.Behaviour research and therapy · 2016Trial
- Heart rate responses to standardized trauma-related pictures in acute posttraumatic stress disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2010Trial
- Effect of PTSD treatment on cardiovascular reactivity during trauma memory recall and correspondence with symptom improvement.European journal of psychotraumatology · 2024Article
- PTSD and depression severity are associated with cardiovascular disease symptoms in trauma-exposed women.European journal of psychotraumatology · 2023Article
- Posttraumatic Stress Disorder (PTSD) as a Risk Factor for Cardiovascular Disease: Implications for Future Research and Clinical Care.Current cardiology reports · 2022Review
- Involvement of the brain-heart axis in the link between PTSD and cardiovascular disease.Depression and anxiety · 2022Review
- The effect of reducing posttraumatic stress disorder symptoms on cardiovascular risk: Design and methodology of a randomized clinical trial.Contemporary clinical trials · 2021Article
- Predictors of chronic trauma-related symptoms in a community sample of New Zealand motor vehicle accident survivors.Culture, medicine and psychiatry · 2012Article
- Cognitive behavioral therapy for the treatment of post-traumatic stress disorder: a review.Neuropsychiatric disease and treatment · 2011Article
- Early heart rate responses to standardized trauma-related pictures predict posttraumatic stress disorder: a prospective study.Psychosomatic medicine · 2010Article
- Posttraumatic stress disorder, cardiovascular, and metabolic disease: a review of the evidence.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2010Review
- Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder.Stress (Amsterdam, Netherlands) · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Persons with posttraumatic stress disorder (PTSD) have been shown to display elevated baseline cardiovascular activity and a heightened physiological reactivity to trauma-related stimuli. Study 1 examined differences in baseline heart rate (HR) and HR reactivity in 68 survivors of motor vehicle accidents (MVAs) and healthy controls without MVA. MVA survivors with PTSD (n=26), subsyndromal PTSD (n=22), traumatized controls without PTSD (non-PTSD with MVA, n=20) and healthy controls without MVA (HC, n=27) underwent measurement of HR during baseline and exposure to a neutral, positive, negative, and trauma-related picture. PTSD patients showed elevated baseline HR and increased HR reactivity only during exposure to the trauma-related picture. Study 2 investigated whether the elevated physiological responses observed in Study 1 normalized after cognitive behavioral therapy (CBT). We conducted a randomized, controlled treatment trial comparing CBT (n=17) to a Wait-list condition (WLC, n=18). Results showed a greater decrease in HR reactivity for CBT than for WLC. The change in HR reactivity was associated with clinical improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.