ArticleClinical and vaccine immunology : CVI2007
Binding of glucuronoxylomannan to the CD14 receptor in human A549 alveolar cells induces interleukin-8 production.
Article in Clinical and vaccine immunology : CVI, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
- Cryptococcosis Associated With Biologic Therapy: A Narrative Review.Open forum infectious diseases · 2024Review
- Human Airway Epithelium Responses to Invasive Fungal Infections: A Critical Partner in Innate Immunity.Journal of fungi (Basel, Switzerland) · 2022Review
- In vitro infection models to study fungal-host interactions.FEMS microbiology reviews · 2021Review
- Mechanisms of fungal dissemination.Cellular and molecular life sciences : CMLS · 2021Review
- An improved staining method of cell cycle analysis with Sybr Green I for fungi:Cell cycle (Georgetown, Tex.) · 2021Article
- Interactions of Extracellular Vesicles from Pathogenic Fungi with Innate Leukocytes.Current topics in microbiology and immunology · 2021Article
- Fine Particulate Matter (PMFrontiers in microbiology · 2020Article
- Animal Models ofFrontiers in immunology · 2020Review
- Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans.Journal of fungi (Basel, Switzerland) · 2018Review
- Cryptococcus-Epithelial Interactions.Journal of fungi (Basel, Switzerland) · 2017Review
- Host cell invasion by medically important fungi.Cold Spring Harbor perspectives in medicine · 2014Review
- Cryptococcus neoformans glucuronoxylomannan fractions of different molecular masses are functionally distinct.Future microbiology · 2014Article
- Can host receptors for fungi be targeted for treatment of fungal infections?Trends in microbiology · 2013Review
- Aimless mutants of Cryptococcus neoformans: failure to disseminate.Fungal biology reviews · 2012Article
- Capsular Material of Cryptococcus neoformans: Virulence and Much More.Mycopathologia · 2012Article
- Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells.Frontiers in microbiology · 2012Article
- Glucuronoxylomannan from Cryptococcus neoformans down-regulates the enzyme 6-phosphofructo-1-kinase of macrophages.The Journal of biological chemistry · 2011Article
- Fungal surface and innate immune recognition of filamentous fungi.Frontiers in microbiology · 2011Article
- TLR4 recognizes Pseudallescheria boydii conidia and purified rhamnomannans.The Journal of biological chemistry · 2010Article
- The still obscure attributes of cryptococcal glucuronoxylomannan.Medical mycology · 2009Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Glucuronoxylomannan (GXM) is the major capsular polysaccharide of Cryptococcus neoformans. GXM receptors have been characterized in phagocytes and endothelial cells, but epithelial molecules recognizing the polysaccharide remain unknown. In the current study, we demonstrate that GXM binds to the CD14 receptor in human type II alveolar epithelial cells, resulting in the production of the proinflammatory chemokine interleukin-8.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.