ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Cell migration along the lateral cortical stream to the developing basal telencephalic limbic system.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 98 citations in OpenAlex.
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- Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.Neuron · 2024Article
- Development and Evolution of Thalamocortical Connectivity.Cold Spring Harbor perspectives in biology · 2024Review
- Which neurodevelopmental processes continue in humans after birth?Frontiers in neuroscience · 2024Article
- Lineage Relationships Between Subpallial Progenitors and Glial Cells in the Piriform Cortex.Frontiers in neuroscience · 2022Article
- A role for sustained MAPK activity in the mouse ventral telencephalon.Developmental biology · 2021Article
- Specific contribution of neurons from the Dbx1 lineage to the piriform cortex.Scientific reports · 2021Article
- The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons.PLoS genetics · 2021Article
- Temporally Distinct Roles for the Zinc Finger Transcription Factor Sp8 in the Generation and Migration of Dorsal Lateral Ganglionic Eminence (dLGE)-Derived Neuronal Subtypes in the Mouse.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Novel Perspectives on the Development of the Amygdala in Rodents.Frontiers in neuroanatomy · 2021Review
- Early Maternal and Social Deprivation Expands Neural Stem Cell Population Size and Reduces Hippocampus/Amygdala-Dependent Fear Memory.Frontiers in neuroscience · 2020Article
- Cortico-Limbic Interactions Mediate Adaptive and Maladaptive Responses Relevant to Psychopathology.The American journal of psychiatry · 2019Review
- Embryonic and postnatal development of mouse olfactory tubercle.Molecular and cellular neurosciences · 2019Article
- The Laminar Organization of Piriform Cortex Follows a Selective Developmental and Migratory Program Established by Cell Lineage.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Development of piriform cortex interhemispheric connections via the anterior commissure: progressive and regressive strategies.Brain structure & function · 2018Article
- Loss of Intercalated Cells (ITCs) in the Mouse Amygdala ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Characterization of Glcci1 expression in a subpopulation of lateral ganglionic eminence progenitors in the mouse telencephalon.Developmental dynamics : an official publication of the American Association of Anatomists · 2018Article
- A Radial Glia Fascicle Leads Principal Neurons from the Pallial-Subpallial Boundary into the Developing Human Insula.Frontiers in neuroanatomy · 2017Article
- Origin of oligodendrocytes in mammalian forebrains: a revised perspective.The journal of physiological sciences : JPS · 2017Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
During embryogenesis, the lateral cortical stream (LCS) emerges from the corticostriatal border (CSB), the boundary between the developing cerebral cortex and striatum. The LCS is comprised of a mix of pallial- and subpallial-derived neural progenitor cells that migrate to the developing structures of the basal telencephalon, most notably the piriform cortex and amygdala. Using a combination of in vitro and in vivo approaches, we analyzed the timing, composition, migratory modes, origin, and requirement of the homeodomain-containing transcription factor Gsh2 (genomic screened homeobox 2) in the development of this prominent migratory stream. We reveal that Pax6 (paired box gene 6)-positive pallial-derived and Dlx2 (distal-less homeobox 2)-positive subpallial-derived subpopulations of LCS cells are generated in distinct temporal windows during embryogenesis. Furthermore, our data indicate the CSB border not only is comprised of separate populations of pallial- and subpallial-derived progenitors that contribute to the LCS but also a subpopulation of cells coexpressing Pax6 and Dlx2. Moreover, despite migrating along a route outlined by a cascade of radial glia, the Dlx2-positive population appears to migrate primarily in an apparent chain-like manner, with LCS migratory cells being generated locally at the CSB with little contribution from other subpallial structures such as the medial, lateral, or caudal ganglionic eminences. We further demonstrate that the generation of the LCS is dependent on the homeodomain-containing gene Gsh2, revealing a novel requirement for Gsh2 in telencephalic development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.