Evidence map›Paper›PMID 17091397›Full record

ReviewJournal of mammary gland biology and neoplasia2006

Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography.

Craig K Abbey, Alexander D Borowsky, Jeffery P Gregg, Robert D Cardiff, Simon R Cherry

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET.Clinical cancer research : an official journal of the American Association for Cancer Research · 2011
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Modeling metastatic breast cancer in mice.Journal of mammary gland biology and neoplasia · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Craig K AbbeyDepartment of Biomedical Engineering, University of California, Davis, CA 95616, USA. Abbey@psych.ucsb.edu
Alexander D Borowsky
Jeffery P Gregg
Robert D Cardiff
Simon R Cherry

Funding

BIOLOGY OF NEOPLASTIC TRANSFORMATION IN BREAST CANCERR01CA089140 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI CARDIFF, ROBERT D · 2001 to 2005
$1.6M
HIGH RESOLUTION PET IMAGING OF MOUSE MODELS OF CANCERR01EB000561 · NIBIB · UNIVERSITY OF CALIFORNIA DAVIS · PI CHERRY, SIMON R · 2002 to 2004
$978k
Quantitative Assessment of Murine Tumors with MicroPET.R21CA102733 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI ABBEY, CRAIG KENDALL · 2003 to 2004
$361k
NCI NIH HHS R01-CA89140NCI NIH HHS R21-CA102733NIBIB NIH HHS R01-EB000561
6 · The paper itself

Abstract

Small-animal imaging with positron emission tomography (PET) has become a valuable tool for evaluating preclinical models of breast cancer and other diseases. In this review, we examine a number of issues related to preclinical imaging studies with PET, using transgenic models of ductal carcinoma in situ and metastasis as specific examples. We discuss imaging components such as reconstruction, normalization, and extraction of quantitative parameters. We also analyze the effect of longitudinal correlations on cohort size and present some simple statistical techniques for determining cohort sizes that may be helpful in designing preclinical imaging studies. We describe studies that are greatly facilitated by access to non-invasive imaging data including a study involving multiple endpoints and another investigating metastasis. We conclude with a brief survey of emerging approaches in small-animal PET imaging.

Indexed as

Fluorodeoxyglucose F18AnimalsCarcinoma, Ductal, BreastCarcinoma in SituDisease Models, AnimalDisease ProgressionLongitudinal StudiesLymphatic MetastasisMammary Glands, AnimalMammary Neoplasms, ExperimentalMicePositron-Emission TomographyWhole-Body CountingFluorodeoxyglucose F18

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.