ReviewPflugers Archiv : European journal of physiology2007
Polarized targeting of ion channels in neurons.
Review in Pflugers Archiv : European journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Sculpting excitable membranes: voltage-gated ion channel delivery and distribution.Nature reviews. Neuroscience · 2025Review
- Article
- Physical principles for scalable neural recording.Frontiers in computational neuroscience · 2013Article
- Long term delivery of pulsed magnetic fields does not alter visual discrimination learning or dendritic spine density in the mouse CA1 pyramidal or dentate gyrus neurons.F1000Research · 2013Article
- Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Actin and microtubule-based cytoskeletal cues direct polarized targeting of proteins in neurons.Science signaling · 2009Review
- Heterologous expression of the invertebrate FMRFamide-gated sodium channel as a mechanism to selectively activate mammalian neurons.Neuroscience · 2008Article
- Genetic dissection of neural circuits.Neuron · 2008Review
- The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons.PloS oneArticle
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Since the time of Cajal it has been understood that axons and dendrites perform distinct electrophysiological functions that require unique sets of proteins [Cajal SR Histology of the nervous system, Oxford University Press, New York, (1995)]. To establish and maintain functional polarity, neurons localize many proteins specifically to either the axonal or the somatodendritic compartment. In particular, ion channels, which are the major regulators of electrical activity in neurons, are often distributed in a polarized fashion. Recently, the ability to introduce tagged proteins into neurons in culture has allowed the molecular mechanisms underlying axon- and dendrite-specific targeting of ion channels to be explored. These investigations have identified peptide signals from voltage-gated Na(+) and K(+) channels that direct trafficking to either axonal or dendritic compartments. In this article we will discuss the molecular mechanisms underlying polarized targeting of voltage-gated ion channels from the Kv4, Kv1, and Na(v)1 families.
Indexed as
Identifiers
17091311What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.