ReviewEuropean journal of pediatrics2007
Familial recurrence of congenital heart disease: an overview and review of the literature.
Review in European journal of pediatrics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Consanguinity and the risk of congenital heart disease.American journal of medical genetics. Part A · 2012Pooled it
- Screening for Structural Heart Defects: A Single-Center Retrospective Cost Analysis for Fetal Echocardiography in Adults with Congenital Heart Disease.Pediatric cardiology · 2026Article
- Utility of Screening Fetal Echocardiograms Following Normal Level II Ultrasounds in Fetuses with Siblings with Congenital Heart Disease.Cardiology and therapy · 2025Article
- Chromosomal analysis and short-term outcome of prenatally diagnosed congenital heart disease.Scientific reports · 2025Article
- Triple repeated fetal congenital heart disease linked to PLD1 mutation: a case report.Journal of medical case reports · 2023Article
- Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome.Cell systems · 2022Article
- Recurrence pattern of non-syndromic familial congenital heart diseases among a large cohort of families from Egypt.BMC pediatrics · 2022Article
- High Familial Recurrence of Congenital Heart Defects in Laterality Defects Patients: An Evaluation of 184 Families.Pediatric cardiology · 2021Observational
- Exome Sequencing and Congenital Heart Disease in Sub-Saharan Africa.Circulation. Genomic and precision medicine · 2021Article
- Genetic Basis of Human Congenital Heart Disease.Cold Spring Harbor perspectives in biology · 2020Article
- Recurrent Congenital Heart Diseases Among Neonates Born to Mothers with Congenital Heart Diseases.Pediatric cardiology · 2019Article
- Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association.Circulation · 2018Review
- Whole-exome sequencing identifies R1279X of MYH6 gene to be associated with congenital heart disease.BMC cardiovascular disorders · 2018Article
- Some Isolated Cardiac Malformations Can Be Related to Laterality Defects.Journal of cardiovascular development and disease · 2018Review
- Appropriate Use of Genetic Testing in Congenital Heart Disease Patients.Current cardiology reports · 2017Review
- Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.PLoS biology · 2016Article
- Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.Human molecular genetics · 2016Article
- Genetic testing in congenital heart disease: A clinical approach.World journal of cardiology · 2016Review
- Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis.Endocrinology · 2015Article
- Risk of congenital heart disease in relatives of probands with conotruncal cardiac defects: an evaluation of 1,620 families.American journal of medical genetics. Part A · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Familial recurrence is one of the classic patterns for the clinical presentation of congenital heart disease (CHD). In recent years, many groups studied empiric recurrence risk in these heart defects, and the aim of this review was to analyse the patterns of inheritance detected in different types of CHD, including atrioventricular canal defect, tetralogy of Fallot, transposition of the great arteries, left-sided obstructions and atrial septal defect. These studies may influence clinical practise guidelines through accurate genetic counselling, but also, they may have important implications in the knowledge of genetic and pathogenetic mechanisms of CHD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.