SynthesisDigestive diseases and sciences2006
Helicobacter pylori infection and gender: a meta-analysis of population-based prevalence surveys.
Synthesis in Digestive diseases and sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 5 syntheses or guidelines pooled it, 205 citations in OpenAlex.
- Systematic review of the relationship of Helicobacter pylori infection with geographical latitude, average annual temperature and average daily sunshine.BMC gastroenterology · 2018Pooled it
- ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.The American journal of gastroenterology · 2017Guideline
- Sequential versus standard triple first-line therapy for Helicobacter pylori eradication.The Cochrane database of systematic reviews · 2016Pooled it
- Optimum duration of regimens for Helicobacter pylori eradication.The Cochrane database of systematic reviews · 2013Pooled it
- Sex hormones, hormonal interventions, and gastric cancer risk: a meta-analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2012Pooled it
- Article
- Association between Helicobacter pylori infection and thyroid dysfunction in adults visiting a tertiary care hospital in Karachi, Pakistan: a cross-sectional study.BMC endocrine disorders · 2026Article
- Helicobacter pylori infection and liver function alterations in individuals undergoing gastric cancer screening: a cohort study.Scientific reports · 2026Article
- EnhancedInfection and immunity · 2026Article
- A mouse model for studying chronicmBio · 2026Article
- Helicobacter pylori seroprevalence and its association with prevalent and incident blood pressure and haemoglobin A1c in the US-based National Longitudinal Study of Adolescent to Adult Health.BMJ public health · 2026Article
- Association ofFrontiers in cellular and infection microbiology · 2026Article
- Vitamin D status andFrontiers in nutrition · 2026Article
- Correlation betweenMicrobiology spectrum · 2025Article
- Prevalence and Diagnostic Comparison ofMicroorganisms · 2025Article
- Helicobacter pylori in the Philippines: Social and Ecological Determinants of Seropositivity and Lack of Association With Systemic Inflammation.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Hallmarks of Cancer Cachexia: Sexual Dimorphism in Related Pathways.International journal of molecular sciences · 2025Review
- Prevalence of Helicobacter pylori infection in the general population in Wuzhou, China: a cross-sectional study.Infectious agents and cancer · 2025Article
- Global trends and future predictions of gastrointestinal ulcers in youth.Frontiers in public health · 2025Article
- Prevalence of Helicobacter pylori cagA virulence factor and validation of serological tests in a population from Northeastern Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although most of Helicobacter pylori-related diseases are associated with male gender, the role of gender as a risk factor for H. pylori infection is still debated. To assess the true association between H. pylori and gender, we conducted a meta-analysis of large, population-based studies where the measure of association had been adjusted at least for age and socioeconomic status, and obtained primary data from authors when information on gender associations were not presented. In 18 adult populations, the test of heterogeneity was not significant and male gender was significantly associated with H. pylori infection (summary odds ratio [OR] 1.16 [95% confidence interval (CI) 1.11, 1.22]). In 10 pediatric populations, the test of heterogeneity was of borderline significance, and the summary OR computed using a random effect model was close to 1 (summary OR 1.03 [95% CI 0.91, 1.17]). This study confirms the male predominance of H. pylori infection in adults as a global and homogeneous phenomenon; such predominance is not apparent in children. Differential antibiotic exposure or differential protective immunity between genders may explain the different results observed between children and adult studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.