ArticlePediatric nephrology (Berlin, Germany)2007
Prescription of drugs blocking the renin-angiotensin system in Italian children.
Article in Pediatric nephrology (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 9 citations in OpenAlex.
- Assessment of the use of angiotensin receptor blockers in major European markets among paediatric population for treating essential hypertension.Journal of human hypertension · 2009Article
- Hypertension in children with chronic kidney disease: pathophysiology and management.Pediatric nephrology (Berlin, Germany) · 2008Review
- Systemic hypertension and proteinuria in childhood chronic renal parenchymal disease: role of antihypertensive drug management.Paediatric drugs · 2007Review
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Authors and funding
14 authors at 9 institutions in 5 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Little is known about the prescription pattern of antihypertensive drugs for children with impaired kidney function. We have therefore documented the use of antihypertensive drugs in this patient group by evaluating the Italian pediatric population-based registry of patients with chronic kidney disease on conservative treatment (ItalKid) from 1995 to 2003. In 1995, prescriptions written for antihypertensive drugs for use by children were approximately equally divided among drugs blocking the renin-angiotensin system and calcium channel blockers (38 vs. 43% of all prescriptions), followed by beta-blockers and diuretics (15 and 4%, respectively). During subsequent years the proportion of prescriptions for drugs blocking the renin-angiotensin system increased (2003: 61%; p<0.001) and that of calcium channel blockers decreased (2003: 18%, p<0.001). In 1995, blockers of the renin-angiotensin system were prescribed, either as monotherapy or in combination, in 53% of the patients, but the relative frequency of the patients prescribed these drugs increased up to 83% in 2003 (p<0.0005). In conclusion, physicians caring for Italian children with impaired kidney function are increasingly prescribing drugs blocking the renin-angiotensin system.
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