Evidence map›Paper›PMID 17088904›Full record

ArticleBritish journal of cancer2006

Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis.

Y C Yang, M L Lu, J Y Rao, H Wallerand, L Cai, W Cao, A Pantuck, G Dalbagni, V Reuter, R A Figlin and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Frontiers in oncology · 2021
    Pooled it
  2. Involvement of FGFR4 Gene Variants on the Clinicopathological Severity in Urothelial Cell Carcinoma.International journal of environmental research and public health · 2019
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Y C YangDepartment of Epidemiology, UCLA School of Public Health and Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA.
M L Lu
J Y Rao
H Wallerand
L Cai
W Cao
A Pantuck
G Dalbagni
V Reuter
R A Figlin
A Belldegrun
C Cordon-Cardo
Z F Zhang
Memorial Sloan Kettering Cancer Center · USUCLA Health · USUniversity of California, Los Angeles · USAssistance Publique – Hôpitaux de Paris · FRFujian Medical University · CNUCLA Jonsson Comprehensive Cancer Center

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
Chemoprevention of Superficial Bladder CancerU01CA096116 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BELLDEGRUN, ARIE S · 2002 to 2005
$4.2M
The UCLA Clinical Nutrition Research UnitP30CA042710 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HEBER, DAVID · 2002 to 2006
$4.0M
VITAMIN/TRACE ELEMENT COREP01CA042710 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HEBER, DAVID NONE · 1985 to 2001
$1.6M
Molecular Epidemiology and Gene-Environment InteractionR21ES011667 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 2002 to 2004
$651k
HELICOBACTER PYLORI MALNUTRITION AND GASTRIC CANCERR03CA077954 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1997 to 1998
–
MOLECULAR EPIDEMIOLOGY OF BLADDER CANCERR01ES006718 · NIEHS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI ZHANG, ZUO-FENG · 1993 to 1995
–
NCI NIH HHS CA09142NCI NIH HHS CA16042NCI NIH HHS CA42710NCI NIH HHS CA96116NCI NIH HHS P01 CA042710NCI NIH HHS P30 CA016042NCI NIH HHS P30 CA042710NCI NIH HHS R03 CA077954NCI NIH HHS T32 CA009142NCI NIH HHS U01 CA096116NIEHS NIH HHS ES 011667NIEHS NIH HHS ES06718NIEHS NIH HHS R21 ES011667
6 · The paper itself

Abstract

The impact of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism on bladder cancer is unknown. We found no clear correlations between the FGFR4 genotype and risk of bladder cancer or pathological parameters. Neither the polymorphism nor TP53 mutation status was an independent predictor of prognosis, but they might act jointly on the disease-specific survival of patients.

Indexed as

AgedDNA Mutational AnalysisFemaleGenes, p53HumansMaleMiddle AgedMutationPolymorphism, Single NucleotidePrognosisReceptor, Fibroblast Growth Factor, Type 4Survival AnalysisSurvival RateUrinary Bladder NeoplasmsFGFR4 protein, humanReceptor, Fibroblast Growth Factor, Type 4

Identifiers

PMID17088904
PMCPMC2360734
OpenAlexW2071500294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.