ArticleCarbohydrate research2007
O-Acetylation in the O-specific polysaccharide isolated from Shigella flexneri serotype 2a.
Article in Carbohydrate research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Evaluation of a QuadrivalentVaccines · 2024Article
- Development of themSphere · 2023Article
- Surface Anchoring of the Kingella kingae Galactan Is Dependent on the Lipopolysaccharide O-Antigen.mBio · 2022Article
- The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate againstACS central science · 2022Article
- Bacteriophage Sf6 host range mutant that infects Shigella flexneri serotype 2a2 strains.FEMS microbiology letters · 2022Article
- Glycoconjugate vaccines againstBiophysical reviews · 2021Review
- Influence of Shigella flexneri 2a O Antigen Acetylation on Its Bacteriophage Sf6 Receptor Activity and Bacterial Interaction with Human Cells.Journal of bacteriology · 2020Article
- Crystal structure of methyl α-l-rhamno-pyranosyl-(1→2)-α-l-rhamno-pyran-oside monohydrate.Acta crystallographica. Section E, Crystallographic communications · 2019Article
- Classical and novel strategies to develop aHuman vaccines & immunotherapeutics · 2019Review
- Serotype-converting bacteriophage SfII encodes an acyltransferase protein that mediates 6-O-acetylation of GlcNAc in Shigella flexneri O-antigens, conferring on the host a novel O-antigen epitope.Journal of bacteriology · 2014Article
- Serotype-conversion in Shigella flexneri: identification of a novel bacteriophage, Sf101, from a serotype 7a strain.BMC genomics · 2014Article
- Serological identification and prevalence of a novel O-antigen epitope linked to 3- and 4-O-acetylated rhamnose III of lipopolysaccharide in Shigella flexneri.Journal of clinical microbiology · 2014Article
- Identification of an O-acyltransferase gene (oacB) that mediates 3- and 4-O-acetylation of rhamnose III in Shigella flexneri O antigens.Journal of bacteriology · 2014Article
- Structural and immunochemical studies of the lipopolysaccharide from the fish pathogen, Aeromonas bestiarum strain K296, serotype O18.Marine drugs · 2013Article
- Progress and pitfalls in Shigella vaccine research.Nature reviews. Gastroenterology & hepatology · 2013Review
- Methyl α-l-rhamnosyl-(1→2)[α-l-rhamnosyl-(1→3)]-α-l-rhamnoside penta-hydrate: synchrotron study.Acta crystallographica. Section E, Structure reports online · 2012Article
- Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV) of Shigella flexneri.BMC biochemistry · 2011Article
- The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis.Clinical lipidology · 2011Article
- Immunochemical studies of Shigella flexneri 2a and 6, and Shigella dysenteriae type 1 O-specific polysaccharide-core fragments and their protein conjugates as vaccine candidates.Carbohydrate research · 2010Article
- Novel myelin penta- and hexa-acetyl-galactosyl-ceramides: structural characterization and immunoreactivity in cerebrospinal fluid.Journal of lipid research · 2010Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Shigella flexneri causes diarrheal diseases especially in infants and children in developing countries. Modifications of the lipopolysaccharide (LPS) molecule, like bacteriophage-mediated glucosylation and acetylation of the O-specific chain (O-SP), are important for the LPS antigenicity and consequently for the immunogenicity of the polysaccharide-based vaccines against shigellosis. Here, we report the degree of O-acetylation and the localisation of O-acetyl groups and side-chain glucose substitution in the O-SP (scheme) in different preparations of S. flexneri type 2a LPS. [structure: see text]
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