ArticleApplied and environmental microbiology2007
Autoinducer-2-producing protein LuxS, a novel salt- and chloride-induced protein in the moderately halophilic bacterium Halobacillus halophilus.
Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Isolation and Characterization of Variants of Quorum-Sensing Signal Molecules in Clinical Acinetobacter baumannii Isolates.Current microbiology · 2026Article
- Halobacillus as source of natural products and enzyme factories.Extremophiles : life under extreme conditions · 2025Review
- Whole Genome Sequencing and Comparative Genomic Analyses ofMicroorganisms · 2020Article
- Physiological Processes Modulated by the Chloride-Sensitive WNK-SPAK/OSR1 Kinase Signaling Pathway and the Cation-Coupled Chloride Cotransporters.Frontiers in physiology · 2020Review
- Saline Environments as a Source of Potential Quorum Sensing Disruptors to Control Bacterial Infections: A Review.Marine drugs · 2019Review
- Arsenic Response of Three AltiplanicFrontiers in microbiology · 2019Article
- Characterization and Salt Response in Recurrent HalotolerantFrontiers in microbiology · 2018Article
- Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus.Frontiers in microbiology · 2014Article
- Quorum sensing in extreme environments.Life (Basel, Switzerland) · 2013Review
- Diketopiperazines produced by the halophilic archaeon, Haloterrigena hispanica, activate AHL bioreporters.Microbial ecology · 2012Article
- The luxS mutation causes loosely-bound biofilms in Shewanella oneidensis.BMC research notes · 2011Article
- Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.Molecular microbiology · 2011Review
- Regulation of osmoadaptation in the moderate halophile Halobacillus halophilus: chloride, glutamate and switching osmolyte strategies.Saline systems · 2008Article
- Glutamate restores growth but not motility in the absence of chloride in the moderate halophile Halobacillus halophilus.Extremophiles : life under extreme conditions · 2007Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The moderately halophilic bacterium Halobacillus halophilus carries a homologue of LuxS, a protein involved in the activated methyl cycle and the production of autoinducer-2, which mediates quorum sensing between certain species. luxS of H. halophilus is part of an operon that encodes an S-adenosylmethionine-dependent methyltransferase, a cysteine synthase, and a beta-cystathionine lyase. Expression of luxS was growth phase dependent, with maximal expression in the mid-exponential growth phase. In addition, transcription of luxS was strictly salt dependent; maximal mRNA concentrations were observed with 2.0 M NaCl in the growth medium. Chloride ions stimulated luxS transcription by a factor of three. Western blot analyses demonstrated a growth phase- and salinity-dependent production of LuxS. Moreover, cellular LuxS levels were strictly chloride dependent. Maximal accumulation of LuxS was observed at 0.5 to 1.0 M Cl(-) and depended on the salinity.
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