ArticleBiophysical journal2007
Temperature effects on DNA chip experiments from surface plasmon resonance imaging: isotherms and melting curves.
Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Design and Assembly of a Cargo-Agnostic Hollow Two-Lidded DNA Origami Box.ACS applied bio materials · 2025Article
- Article
- Ionic Strength and Hybridization Position near Gold Electrodes Can Significantly Improve Kinetics in DNA-Based Electrochemical Sensors.ACS applied materials & interfaces · 2023Article
- Kinetics of Isothermal Dumbbell Exponential Amplification: Effects of Mix Composition on LAMP and Its Derivatives.Biosensors · 2022Article
- Melting Curve Analysis of Aptachains: Adenosine Detection with Internal Calibration.Biosensors · 2021Article
- Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics.Nature communications · 2019Article
- Simultaneous Profiling of DNA Mutation and Methylation by Melting Analysis Using Magnetoresistive Biosensor Array.ACS nano · 2017Article
- Magnetoresistive sensors for measurements of DNA hybridization kinetics - effect of TINA modifications.Scientific reports · 2017Article
- SPR and SPR Imaging: Recent Trends in Developing Nanodevices for Detection and Real-Time Monitoring of Biomolecular Events.Sensors (Basel, Switzerland) · 2016Review
- Surface vs. solution hybridization: effects of salt, temperature, and probe type.Chemical communications (Cambridge, England) · 2015Article
- Physico-chemical foundations underpinning microarray and next-generation sequencing experiments.Nucleic acids research · 2013Review
- Melting thermodynamics of reversible DNA/ligand complexes at interfaces.Journal of the American Chemical Society · 2012Article
- Synthesis and chromatography-free purification of PNA-PEO conjugates for the functionalisation of gold sensors.Molecules (Basel, Switzerland) · 2012Article
- Thermostable DNA immobilization and temperature effects on surface hybridization.Langmuir : the ACS journal of surfaces and colloids · 2012Article
- Accurate prediction of binding thermodynamics for DNA on surfaces.The journal of physical chemistry. B · 2011Article
- Kinetic mechanisms in morpholino-DNA surface hybridization.Journal of the American Chemical Society · 2011Article
- Microfluidics-based lab-on-chip systems in DNA-based biosensing: an overview.Sensors (Basel, Switzerland) · 2011Review
- Salt concentration effects on equilibrium melting curves from DNA microarrays.Biophysical journal · 2010Article
- Molecular mechanisms in morpholino-DNA surface hybridization.Journal of the American Chemical Society · 2010Article
- Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging.Nucleic acids research · 2009Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present an analysis of hybridization experiments on a DNA chip studied by surface plasmon resonance imaging. The reaction constants at various temperatures and for different probe lengths are obtained from Langmuir isotherms and hybridization kinetics. The melting curves from temperature scans are also obtained without any labeling of the targets. The effects of the probe length on the hybridization thermodynamics, deduced from the temperature dependence of the reaction constants as well as from the melting curves, suggest dispersion in the length of the hybridization segments of the probes accessible to the targets. Those are, however, sufficient to suggest efficient point mutation detection from temperature scans.
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