Evidence map›Paper›PMID 17083142›Full record

ReviewProteomics2006

Human body fluid proteome analysis.

Shen Hu, Joseph A Loo, David T Wong

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Proteomics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02023502 (Proteomic Pattern in Female Stress Urinary Incontinence), which is not on this map. Cited by 169 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed, 3 pooled it
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02023502 completednot on this mapstarted 2013, after this paper: background citation

Proteomic Pattern in Female Stress Urinary Incontinence: a Pilot Study

TypeobservationalSponsorMedical University of ViennaRan2013 to 2015Enrolled40ConditionsFemale Stress Urinary IncontinenceArmscollection of urine and blood sample
3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 3 syntheses or guidelines pooled it, 526 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Proteomic Analysis of Biological Fluids.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Peptidome Profiling ofAntibiotics (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shen HuSchool of Dentistry, Division of Oral Biology and Medicine, Dental Research Institute, University of California, Los Angeles, CA 90095, USA. shenhu@ucla.edu
Joseph A Loo
David T Wong
University of California, Los Angeles · US

Funding

Human Salivary ProteomeU01DE016275 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2004 to 2007
$5.5M
Salivary Proteomic & Genomic Biomarkers for Primary Sjogren's SyndromeR01DE017593 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2006 to 2010
$2.1M
Genomics and Proteomics of Oral Precancer ProgressionR01DE015970 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2004 to 2009
$1.9M
NIDCR NIH HHS R01 DE015970NIDCR NIH HHS R01 DE017593NIDCR NIH HHS R01-DE15970NIDCR NIH HHS R01-DE17593NIDCR NIH HHS U01 DE016275NIDCR NIH HHS U01-DE016275
6 · The paper itself

Abstract

The focus of this article is to review the recent advances in proteome analysis of human body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, and amniotic fluid, as well as its applications to human disease biomarker discovery. We aim to summarize the proteomics technologies currently used for global identification and quantification of body fluid proteins, and elaborate the putative biomarkers discovered for a variety of human diseases through human body fluid proteome (HBFP) analysis. Some critical concerns and perspectives in this emerging field are also discussed. With the advances made in proteomics technologies, the impact of HBFP analysis in the search for clinically relevant disease biomarkers would be realized in the future.

Indexed as

ProteomicsAcute-Phase ProteinsAmniotic FluidBiomarkersBlood ProteinsBody FluidsBronchoalveolar Lavage FluidCerebrospinal Fluid ProteinsFemaleGene Expression ProfilingGlycoproteinsHumansLipoproteinsNipplesPregnancyProtein Array AnalysisAcute-Phase ProteinsBiomarkersBlood ProteinsCerebrospinal Fluid ProteinsGlycoproteinsLipoproteinsSalivary Proteins and Peptides

Identifiers

PMID17083142
PMCPMC2910092
OpenAlexW1972395654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.