ArticleNucleic acids research2007
NATsDB: Natural Antisense Transcripts DataBase.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed.
- NanoPrePro: a fully equipped, fast, and memory-efficient preprocessor for nanopore transcriptomic sequencing.Briefings in bioinformatics · 2026Article
- Bone metastasis in non-small-cell lung cancer: genomic characterization and exploration of potential targets.Therapeutic advances in medical oncology · 2024Article
- Promoter switching in response to changing environment and elevated expression of protein-coding genes overlapping at their 5' ends.Scientific reports · 2021Article
- Time dependent differential regulation of a novel long non-coding natural antisense RNA during long-term memory formation.Scientific reports · 2021Article
- PTB-AS, a Novel Natural Antisense Transcript, Promotes Glioma Progression by Improving PTBP1 mRNA Stability with SND1.Molecular therapy : the journal of the American Society of Gene Therapy · 2019Article
- OverGeneDB: a database of 5' end protein coding overlapping genes in human and mouse genomes.Nucleic acids research · 2018Article
- The temporal expression profile of a Nos3-related natural antisense RNA in the brain suggests a possible role in neurogenesis.Nitric oxide : biology and chemistry · 2017Article
- NATpipe: an integrative pipeline for systematical discovery of natural antisense transcripts (NATs) and phase-distributed nat-siRNAs from de novo assembled transcriptomes.Scientific reports · 2016Article
- Long non-coding RNAs as novel expression signatures modulate DNA damage and repair in cadmium toxicology.Scientific reports · 2015Article
- Splicing of a non-coding antisense transcript controls LEF1 gene expression.Nucleic acids research · 2015Article
- A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression.Scientific reports · 2015Article
- Genome-wide view of natural antisense transcripts in Arabidopsis thaliana.DNA research : an international journal for rapid publication of reports on genes and genomes · 2015Article
- Contribution of natural antisense transcription to an endogenous siRNA signature in human cells.BMC genomics · 2014Article
- HMGA1-pseudogene overexpression contributes to cancer progression.Cell cycle (Georgetown, Tex.) · 2014Review
- Asymmetric localization of natural antisense RNA of neuropeptide sensorin in Aplysia sensory neurons during aging and activity.Frontiers in genetics · 2014Article
- Genome-wide identification, characterization, and expression analysis of lineage-specific genes within zebrafish.BMC genomics · 2013Article
- Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer.Cell research · 2012Article
- Article
- Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae.RNA (New York, N.Y.) · 2012Article
- Transcriptional regulation of translocator protein (Tspo) via a SINE B2-mediated natural antisense transcript in MA-10 Leydig cells.Biology of reproduction · 2012Article
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Authors and funding
6 authors.
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Abstract
Natural antisense transcripts (NATs) are reverse complementary at least in part to the sequences of other endogenous sense transcripts. Most NATs are transcribed from opposite strands of their sense partners. They regulate sense genes at multiple levels and are implicated in various diseases. Using an improved whole-genome computational pipeline, we identified abundant cis-encoded exon-overlapping sense-antisense (SA) gene pairs in human (7356), mouse (6806), fly (1554), and eight other eukaryotic species (total 6534). We developed NATsDB (Natural Antisense Transcripts DataBase, http://natsdb.cbi.pku.edu.cn/) to enable efficient browsing, searching and downloading of this currently most comprehensive collection of SA genes, grouped into six classes based on their overlapping patterns. NATsDB also includes non-exon-overlapping bidirectional (NOB) genes and non-bidirectional (NBD) genes. To facilitate the study of functions, regulations and possible pathological implications, NATsDB includes extensive information about gene structures, poly(A) signals and tails, phastCons conservation, homologues in other species, repeat elements, expressed sequence tag (EST) expression profiles and OMIM disease association. NATsDB supports interactive graphical display of the alignment of all supporting EST and mRNA transcripts of the SA and NOB genes to the genomic loci. It supports advanced search by species, gene name, sequence accession number, chromosome location, coding potential, OMIM association and sequence similarity.
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Registered trials
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