ArticleJournal of clinical microbiology2007
Helicobacter cinaedi cellulitis and bacteremia in immunocompetent hosts after orthopedic surgery.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Infected aortic aneurysm caused by Helicobacter cinaedi: case series and systematic review of the literature.BMC infectious diseases · 2020Pooled it
- Article
- CAIP-Induced ROS Production Contributes to Sustaining Atherosclerotic Process Associated withInternational journal of molecular sciences · 2024Article
- Helicobacter cinaedi bacteraemia secondary to enterocolitis in an immunocompetent patient.Gut pathogens · 2021Article
- Infections With Enterohepatic Non-Frontiers in cellular and infection microbiology · 2021Review
- Helicobacter cinaedi-Associated Refractory Cellulitis in Patients with X-Linked Agammaglobulinemia.Journal of clinical immunology · 2020Article
- Genome Sequencing Verifies Relapsed Infection ofOpen forum infectious diseases · 2019Article
- First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm.BMC infectious diseases · 2019Article
- A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid.Clinical medicine insights. Case reports · 2019Article
- Multi-step genomic dissection of a suspected intra-hospital Helicobacter cinaedi outbreak.Microbial genomics · 2018Article
- Unique Cellulitis: Helicobacter cinaedi.Internal medicine (Tokyo, Japan) · 2018Article
- Mutations in Genes Encoding Penicillin-Binding Proteins and Efflux Pumps Play a Role in β-Lactam Resistance in Helicobacter cinaedi.Antimicrobial agents and chemotherapy · 2018Article
- A Case Of RecurrentJournal of bone and joint infection · 2018Article
- Helicobacter cinaedi bacteremia with cellulitis in a living-donor kidney transplant recipient identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry: a case report.BMC research notes · 2017Article
- The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells.Scientific reports · 2017Article
- Bacteremia and Skin Infections in Four Patients Caused byOpen forum infectious diseases · 2017Article
- Article
- Epithelial Coculture and l-Lactate Promote Growth of Helicobacter cinaedi under H2-Free Aerobic Conditions.Applied and environmental microbiology · 2016Article
- The pathogenic potential of Helicobacter cinaedi isolated from non-human sources: adherence, invasion and translocation ability in polarized intestinal epithelial Caco-2 cells in vitro.The Journal of veterinary medical science · 2016Article
- Helicobacter cinaedi knee infection after arthroscopy in an immunocompetent patient.BMJ case reports · 2015Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At various times after orthopedic operations (more than a few weeks, with an average of 29.9 days), 11 patients had a sudden onset of high temperature (average 38.9 degrees C) and local cellulitis at different sites on the operated sides. The wounds had completely healed, without complicated infections, when the cellulitis occurred. The clinical picture of cellulitis in all patients was atypical: diffuse salmon-pink skin color, local heat, swelling, spontaneous pain, and tenderness but no eruptions. No patient had any underlying immunocompromising conditions or had been given immunosuppressive agents. Gram-negative spiral bacteria were isolated from blood cultures and were identified as Helicobacter cinaedi on the basis of 16S rRNA gene sequencing and DNA-DNA hybridization using standard strains. By means of phylogenetic analysis, we divided these clinical isolates into two clones. The H. cinaedi strain isolated via fecal cultures from two patients without intestinal symptoms was the same clone as the blood isolate. All isolates were quite susceptible to various antibiotics, and clinical and inflammatory symptoms of bacteremia and cellulitis improved after treatment with penicillins and cephalosporins. A relatively high incidence of recurrence of the same disease was observed, however. Almost all patients responded immunologically to the infection, as evidenced by the production of serum antibody against H. cinaedi. We thus suggest that H. cinaedi should not be regarded as simply an opportunistic pathogen but that it may be a pathogen in immunocompetent hosts and may cause infections together with bacteremia and cellulitis.
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