Evidence map›Paper›PMID 17079432›Full record

ArticleClinical and vaccine immunology : CVI2007

Rapid expression of Mycobacterium avium subsp. paratuberculosis recombinant proteins for antigen discovery.

Lingling Li, Shirin Munir, John P Bannantine, Srinand Sreevatsan, Sagarika Kanjilal, Vivek Kapur

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Encapsulins.Annual review of biochemistry · 2022
    Review
  2. Article
  3. Article
  4. Article
  5. Pathogenesis, Molecular Genetics, and Genomics ofFrontiers in veterinary science · 2017
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lingling LiDepartment of Microbiology, University of Minnesota, 1500 Gortner Ave., St. Paul, MN 55108, USA.
Shirin Munir
John P Bannantine
Srinand Sreevatsan
Sagarika Kanjilal
Vivek Kapur
University of Minnesota · USNational Animal Disease Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium avium subsp. paratuberculosis is the causative agent of Johne's disease, a chronic granulomatous enteritis of ruminants and other species. Detection of infection in animals is hampered by the lack of sensitive and specific diagnostic assays. We describe here an approach that utilizes translationally active PCR fragments for the rapid in vitro transcription and translation of recombinant proteins for antigen discovery in M. avium subsp. paratuberculosis. The investigations showed that the MAP1272c protein selectively reacts with sera from Johne's disease-positive cattle and represents an antigen of potential utility in M. avium subsp. paratuberculosis immunodiagnostics.

Indexed as

AnimalsAntigens, BacterialCattleMycobacterium avium subsp. paratuberculosisParatuberculosisPolymerase Chain ReactionRecombinant Fusion ProteinsAntigens, BacterialRecombinant Fusion Proteins

Identifiers

PMID17079432
PMCPMC1797714
OpenAlexW2119589149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.