Evidence map›Paper›PMID 17077393›Full record

ArticleAmerican journal of public health2006

Advances in medical technology and creation of disparities: the case of Down syndrome.

Babak Khoshnood, Catherine De Vigan, Véronique Vodovar, Gérard Bréart, François Goffinet, Béatrice Blondel

Abstract read
In one paragraph

Article in American journal of public health, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Babak KhoshnoodUnit on Perinatal and Women's Health, Institut National de la Santé et de la Recherche Médicale (INSERM), U149, Paris, France. khoshnood@vjf.inserm.fr
Catherine De Vigan
Véronique Vodovar
Gérard Bréart
François Goffinet
Béatrice Blondel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe assessed socioeconomic differences in probabilities of prenatal diagnoses of Down syndrome and continuation of pregnancies after such diagnoses, along with the effects of these differences on disparities in live-birth prevalences of Down syndrome.

methodsUsing population-based data derived from 1433 cases of Down syndrome and 3731 control births, we assessed age-adjusted effects of maternal occupation and geographic origin on prenatal diagnoses, as well as overall and live-birth odds, of Down syndrome.

resultsMaternal occupation and geographic origin had significant effects on the probability of a prenatal diagnosis of Down syndrome and on continuation of pregnancy after such a diagnosis. Women in lower-status occupational categories had higher odds of delivering a live-born infant with Down syndrome. In comparison with women in the highest-status occupational category, the age-adjusted odds ratio for a Down syndrome live birth among women without an occupation was 2.4 (95% confidence interval [CI] = 1.7, 3.3). By contrast, there were no disparities in age-adjusted overall likelihood of Down syndrome.

conclusionsSocioeconomic differences in use of prenatal testing have created disparities in the live-birth prevalence of Down syndrome. Overall Down syndrome risk does not vary according to socioeconomic status.

Indexed as

Pregnancy OutcomeSocioeconomic FactorsAbortion, EugenicAdultBiomedical TechnologyDown SyndromeFemaleGeographyHealth Services AccessibilityHumansInfant, NewbornLogistic ModelsMaternal AgeMiddle AgedOccupationsParis

Identifiers

PMID17077393
PMCPMC1698165

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.