Evidence map›Paper›PMID 17073085›Full record

ArticleEmerging infectious diseases2006

Predominance of ancestral lineages of Mycobacterium tuberculosis in India.

M Cristina Gutierrez, Niyaz Ahmed, Eve Willery, Sujatha Narayanan, Seyed E Hasnain, Devendra S Chauhan, Vishwa M Katoch, Véronique Vincent, Camille Locht, Philip Supply

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Dynamics ofPathogens (Basel, Switzerland) · 2022
    Article
  6. Article
  7. A comparative analysis of molecular genotypes ofFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. SARS-CoV-2 infection in India bucks the trend: Trained innate immunity?American journal of human biology : the official journal of the Human Biology Council · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Whole Genome Sequencing ofFrontiers in microbiology · 2019
    Article
  14. Molecular clustering of patients withJournal of clinical tuberculosis and other mycobacterial diseases · 2018
    Article
  15. Article
  16. Diversity ofBioMed research international · 2018
    Article
  17. Mycobacterium tuberculosis Whole Genome Sequences From Southern India Suggest Novel Resistance Mechanisms and the Need for Region-Specific Diagnostics.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M Cristina GutierrezInstitut Pasteur, Paris, France.
Niyaz Ahmed
Eve Willery
Sujatha Narayanan
Seyed E Hasnain
Devendra S Chauhan
Vishwa M Katoch
Véronique Vincent
Camille Locht
Philip Supply

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although India has the highest prevalence of tuberculosis (TB) worldwide, the genetic diversity of Mycobacterium tuberculosis in India is largely unknown. A collection of 91 isolates originating from 12 different regions spread across the country were analyzed by genotyping using 21 loci with variable-number tandem repeats (VNTRs), by spoligotyping, by principal genetic grouping (PGG), and by deletion analysis of M. tuberculosis-specific deletion region 1. The isolates showed highly diverse VNTR genotypes. Nevertheless, highly congruent groupings identified by using the 4 independent sets of markers permitted a clear definition of 3 prevalent PGG1 lineages, which corresponded to the "ancestral" East African-Indian, the Delhi, and the Beijing/W genogroups. A few isolates from PGG2 lineages and a single representative of the presumably most recent PGG3 were identified. These observations suggest a predominance of ancestral M. tuberculosis genotypes in the Indian subcontinent, which supports the hypothesis that India is an ancient endemic focus of TB.

Indexed as

Evolution, MolecularGenetic VariationAdultDNA, BacterialFemaleGenotypeHumansIndiaMaleMiddle AgedMinisatellite RepeatsMycobacterium tuberculosisOligonucleotidesPolymorphism, Single NucleotideTuberculosisDNA, BacterialOligonucleotides

Identifiers

PMID17073085
PMCPMC3294724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.