ArticlePediatric radiology2007
Chest CT findings in pediatric Wegener's granulomatosis.
Article in Pediatric radiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 32 citations in OpenAlex.
- Utilizing a chest CT interstitial lung disease scoring system for commonly encountered pediatric rheumatologic diseases with associated interstitial lung disease with clinical correlation.Pediatric radiology · 2026Article
- Imaging of systemic vasculitis in childhood.Pediatric radiology · 2015Review
- Asymptomatic intracardiac mass in a 14-year-old girl with granulomatosis with polyangiitis: Case report.Pediatric rheumatology online journal · 2012Article
- Distinguishing Wegener's granulomatosis from necrotizing community acquired pneumonia: A case report and comparison of radiographic findings.Pediatric pulmonology · 2009Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough pulmonary involvement occurs in the majority of children and adolescents with Wegener's granulomatosis (WG), relatively little has been published regarding the CT imaging manifestations in this group of patients.
objectiveTo determine the frequency and types of chest CT abnormalities in active pediatric WG (pWG). MATERIALS AND
methodsThe study was a retrospective examination of 29 chest CT examinations performed at diagnosis (n=14) and during disease flares (n=15) in 18 children.
resultsThe most common abnormalities were nodules (seen in 90% of examinations), ground-glass opacification (52%), and air-space opacification (45%). Of examinations with nodules, 73% demonstrated nodules >5 mm in diameter and 69% demonstrated more than five nodules; 17% had cavitary lesions. The only abnormality with a significant difference in prevalence between diagnosis and disease flares was air-space opacification, present in 71% and 20%, respectively (P < 0.01).
conclusionsIn accordance with the findings of published adult studies and at variance with those of prior pediatric studies, our findings indicate that chest CT abnormalities in active pWG are frequent, most commonly comprising nodules and ground-glass opacification, which may be difficult to detect on plain radiography. We therefore advocate the routine use of chest CT for all affected patients, both at the time of presentation and during disease flares.
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