ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2006
[Regional growth preferences in hereditary, synchronous, and metachronous colorectal carcinomas. Basics of tumor surgery Part II].
Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- [Surgical aspects of indications and techniques for adenomatous polyposis variants].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Review
- Surgical considerations in FAP-related pouch surgery: Could we do better?Familial cancer · 2016Review
- [Prediction of prognosis of pancreatic cancer based on the homing area].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2013Article
- [Spontaneous change of malignancy of solid malignant tumors : statistical investigations of colorectal and pancreatic carcinoma].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2012Review
- Ninety and still active in research.Langenbeck's archives of surgery · 2012Article
- [The adenoma-carcinoma sequence model--an interruption. Comment on the contributions by F. Stelzner].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2006Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article discusses the therapeutic importance of the loss of self-regulation of cell division in polypoid adenomas and in the cloacogenic, cancerophilic rectal segment. Regional growth preferences can observed in familial adenomatous polyposis (FAP) and ulcerative colitis, as in other diseases featuring a cancerous disposition on the mucosa. For example, rectal carcinomas are more common than colon carcinomas if one considers the total mucosal surface area at risk. Malignant changes do not occur randomly in existing adenomas of FAP patients, and the adenomas' cell division--as in other adenomas--is governed by some degree of self-regulation. In FAP patients undergoing proctocolectomy, preferred new growth areas for carcinomas include the duodenum and ileum. In patients with synchronous colorectal cancers, the rectum is more commonly affected than other colon segments. If the rectum is resected, metachronous carcinomas are exceedingly rare in the remaining colon segments. Clinical decisions about rectal resection must be informed by understanding of the importance of this organ for anorectal continence as well as the described growth of colorectal malignancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.