Evidence map›Paper›PMID 17071715›Full record

ArticleNucleic acids research2007

EPConDB: a web resource for gene expression related to pancreatic development, beta-cell function and diabetes.

Joan M Mazzarelli, John Brestelli, Regina K Gorski, Junmin Liu, Elisabetta Manduchi, Deborah F Pinney, Jonathan Schug, Peter White, Klaus H Kaestner, Christian J Stoeckert

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. EuPathDB: the eukaryotic pathogen database.Nucleic acids research · 2013
    Article
  5. Article
  6. Article
  7. EuroDia: a beta-cell gene expression resource.Database : the journal of biological databases and curation · 2010
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Joan M MazzarelliDepartment of Genetics, School of Medicine, Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, USA.
John Brestelli
Regina K Gorski
Junmin Liu
Elisabetta Manduchi
Deborah F Pinney
Jonathan Schug
Peter White
Klaus H Kaestner
Christian J Stoeckert
University of Pennsylvania · US

Funding

PHS HHS UO1 56947
6 · The paper itself

Abstract

EPConDB (http://www.cbil.upenn.edu/EPConDB) is a public web site that supports research in diabetes, pancreatic development and beta-cell function by providing information about genes expressed in cells of the pancreas. EPConDB displays expression profiles for individual genes and information about transcripts, promoter elements and transcription factor binding sites. Gene expression results are obtained from studies examining tissue expression, pancreatic development and growth, differentiation of insulin-producing cells, islet or beta-cell injury, and genetic models of impaired beta-cell function. The expression datasets are derived using different microarray platforms, including the BCBC PancChips and Affymetrix gene expression arrays. Other datasets include semi-quantitative RT-PCR and MPSS expression studies. For selected microarray studies, lists of differentially expressed genes, derived from PaGE analysis, are displayed on the site. EPConDB provides database queries and tools to examine the relationship between a gene, its transcriptional regulation, protein function and expression in pancreatic tissues.

Indexed as

Databases, GeneticTranscription, GeneticAnimalsBinding SitesDiabetes MellitusGene Expression ProfilingHumansInsulin-Secreting CellsInternetMiceOligonucleotide Array Sequence AnalysisPancreasPromoter Regions, GeneticSoftwareTranscription FactorsUser-Computer InterfaceTranscription Factors

Identifiers

PMID17071715
PMCPMC1781120
OpenAlexW2068141142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.