ArticleAmerican journal of respiratory and critical care medicine2007
Informal caregiver burden among survivors of prolonged mechanical ventilation.
Article in American journal of respiratory and critical care medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review.Anaesthesiology intensive therapy · 2023Pooled it
- Instrumental Activities of Daily Living after Critical Illness: A Systematic Review.Annals of the American Thoracic Society · 2017Pooled it
- A Pilot Randomized Controlled Trial Assessing the Feasibility and Acceptability of Family-Partnered Delirium Prevention, Detection, and Management in Critically Ill Adults: The Activating Family Caregivers in the Identification Prevention and Management of Delirium (ACTIVATE) Study.Critical care explorations · 2025Trial
- Post-Intensive Care Syndrome and Caregiver Burden: A Post Hoc Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- The Association between Patient Health Status and Surrogate Decision Maker Post-Traumatic Stress Disorder Symptoms in Chronic Critical Illness.Annals of the American Thoracic Society · 2021Trial
- Trial
- Early mobilization in pediatric critical care and parental psychological outcomes 3-6 months after discharge-a pilot study.European journal of pediatrics · 2026Article
- Longitudinal Changes in Symptoms of Post-Intensive Care Syndrome: A Secondary Analysis of a Scoping Review.JMA journal · 2025Review
- Exploring the Landscape of Social and Economic Factors in Critical Illness Survivorship: A Scoping Review.Critical care explorations · 2025Article
- Identification of unmet information needs among families of critically ill patients and their association with post-intensive care syndrome-family: protocol for a single-center cross-sectional study.BMC palliative care · 2025Article
- Identifying the burdens for informal caregivers of tracheostomy-dependent people: a scoping review protocol.BMJ open · 2025Article
- Post-Intensive Care Syndrome Family.Critical care clinics · 2025Review
- Post-Intensive Care Syndrome as a Burden for Patients and Their Caregivers: A Narrative Review.Journal of clinical medicine · 2024Review
- Burden, social support, and coping strategies in family caregivers of individuals receiving home mechanical ventilation: a cross-sectional study.BMC nursing · 2024Article
- When chronic critical illness is a family affair: A multi-perspective qualitative study of family involvement in long-term care.Chronic illness · 2023Article
- Implementation of video-calls between patients admitted to intensive care unit during the COVID-19 pandemic and their families: a pilot study of psychological effects.Journal of anesthesia, analgesia and critical care · 2022Article
- ProPACC: Protocol for a Trial of Integrated Specialty Palliative Care for Critically Ill Older Adults.Journal of pain and symptom management · 2022Article
- Mental health symptoms in family members of COVID-19 ICU survivors 3 and 12 months after ICU admission: a multicentre prospective cohort study.Intensive care medicine · 2022Article
- Stress on caregivers providing prolonged mechanical ventilation patient care in different facilities: A cross-sectional study.PloS one · 2022Article
- Heart rate variability and subsequent psychological distress among family members of intensive care unit patients.The Journal of international medical research · 2021Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
rationaleAlthough caregiver burden is well described in chronic illness, few studies have examined burden among caregivers of survivors of critical illness. In existing studies, it is unclear whether the observed burden is a consequence of critical illness or of preexisting patient illness.
objectivesTo describe 1-yr longitudinal outcomes for caregivers of patients who survived critical illness, and to compare depression risk between caregivers of patients with and without pre-intensive care unit (ICU) functional dependency.
methodsProspective, parallel, cohort study of survivors of prolonged (greater than 48 h) mechanical ventilation and their informal caregivers. Caregivers were divided into two cohorts on the basis of whether patients were functionally independent (n = 99, 59%), or dependent (n = 70, 41%) before admission. Functional dependency was defined as dependency in one or more activities of daily living or in three or more instrumental activities of daily living. Patient and caregiver outcomes were measured 2, 6, and 12 mo after mechanical ventilation initiation. MEASUREMENTS AND MAIN
resultsWe studied three caregiver outcomes: depression risk, lifestyle disruption, and employment reduction. Most patients were male (59.8%), with a mean (SD) age of 56.6 (19.0) yr. Caregivers were mostly female (75.7%), with a mean (SD) age of 54.6 (14.7) yr. Prevalence of caregiver depression risk was high at all time points (33.9, 30.8, and 22.8%; p = 0.83) and did not vary by patient pre-ICU functional status. Lifestyle disruption and employment reduction were also common and persistent.
conclusionsDepression symptoms, lifestyle disruption, and employment reduction were common among informal caregivers of critical illness survivors. Depression risk was high regardless of patient pre-ICU functional status.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.