Evidence map›Paper›PMID 17067397›Full record

ArticleBMC cardiovascular disorders2006

Smoking status and common carotid artery intima-medial thickness among middle-aged men and women based on ultrasound measurement: a cohort study.

Amy Z Fan, Maura Paul-Labrador, C Noel Bairey Merz, Carlos Iribarren, James H Dwyer

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  4. Impact of different antihypertensives on carotid arterial wall thickness.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Observational
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  12. Relationship between inflammatory markers, endothelial activation markers, and carotid intima-media thickness in HIV-infected patients receiving antiretroviral therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2009 · on this map
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amy Z FanPrevention Research Center, Pacific Institute for Research and Evaluation, Berkeley, CA, USA. afan@prev.org
Maura Paul-Labrador
C Noel Bairey Merz
Carlos Iribarren
James H Dwyer

Funding

INTIMAL THICKENING &ANTITOXIDANTS IN HISPANICS &ANGLOSR01HL049910 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DWYER, JAMES H · 1994 to 2003
$3.2M
NHLBI NIH HHS HL49910NHLBI NIH HHS R01 HL049910
6 · The paper itself

Abstract

backgroundCigarette smoking is an established causal factor for atherosclerosis. However, the smoking effect on different echogenic components of carotid arterial wall measured by ultrasound is not well elucidated.

methodsMiddle-aged men and women who had IMT measurement > or = 0.7 mm at baseline and follow-up were included (N = 413, age 40-60 years at baseline in 1995). Intima-media thickness of common carotid artery (CCA-IMT) and its components (echogenic and echolucent layers) were measured at baseline and in the follow-up examination 3 years later. IMT and its components were compared across current, former and never smokers. Individual growth models were used to examine how smoking status was related to the baseline and progression of overall IMT and IMT components.

resultsFor both men and women, current smoking was associated with thicker echogenic layer than never smokers; former smokers exhibited thinner echogenic layer than current smokers after adjustment for cigarette pack-years. Among women, current smoking was also associated with a thinned echolucent layer that resulted in a non-significant overall association of current smoking with IMT for women.

conclusionCigarette smoking is associated with carotid artery morphological changes and the association is sex-dependent. The atherogenic effect of smoking appears to be partly reversible among former smokers. IMT measurement alone may not be adequate to detect carotid atherosclerosis associated with cigarette smoking among middle-age women.

Indexed as

AdultCarotid Artery, CommonFemaleHumansMaleMiddle AgedSmokingTunica IntimaTunica MediaUltrasonography

Identifiers

PMID17067397
PMCPMC1634872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.