ArticleThe Histochemical journal1990
Catecholamine-synthesizing enzymes and neuropeptides in rat heart epicardial ganglia; an immunohistochemical study.
Article in The Histochemical journal, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- Distribution and morphology of calcitonin gene-related peptide (CGRP) innervation in flat mounts of whole rat atria and ventricles.Autonomic neuroscience : basic & clinical · 2024Article
- Clinical potential of sensory neurites in the heart and their role in decision-making.Frontiers in neuroscience · 2023Review
- Therapeutic potential of Pnmt+ primer cells for neuro/myocardial regeneration.American journal of stem cells · 2013Review
- Immunohistochemical characterization of the intrinsic cardiac neural plexus in whole-mount mouse heart preparations.Heart rhythm · 2011Article
- Distinctive left-sided distribution of adrenergic-derived cells in the adult mouse heart.PloS one · 2011Article
- Modulation of rat parasympathetic cardiac ganglion phenotype and NGF synthesis by adrenergic nerves.Autonomic neuroscience : basic & clinical · 2009Article
- Article
- Catecholaminergic neurons in the rat intrinsic cardiac nervous system.Neurochemical research · 2003Article
- Distribution of the hypothalamic cardioactive hormone "G"-protein complex (PCG) in neuronal elements of the heart in intact and vagotomized rats.Neurochemical research · 2002Article
- Comparative morphology, cytochemistry and innervation of chromaffin tissue in vertebrates.Journal of anatomy · 1993Article
- Immunocytochemical localisation of substance P-like nerves in the cardiac ganglia of the monkey (Macaca fascicularis).Journal of anatomy · 1992Article
- Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The subepicardial atrial ganglia of rat hearts were examined using immunohistochemical techniques and antibodies against the catecholamine-synthetic enzymes tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (DBH), and the neuropeptides substance P (SP), calcitonin gene-related peptide (CGRP), neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP) and met-5-enkephalin (ENK). Some of the ganglion cells present in the ganglia exhibited DBH-like immunoreactivity (LI) and NPY-LI, whilst these cells never exhibited TH-, VIP-, CGRP-, SP- or ENK-LI. Groups of small cells exhibiting an intense TH-LI, corresponding to cells referred to as catecholamine-containing cells and sometimes small intensely fluorescent cells in the literature, were observed in the ganglia. A subpopulation of these cells exhibited immunoreactivity to one of the neuropeptides tested, namelyu SP. Only a few of the cells showing TH-LI displayed DBH-LI. Nerve fibres showing SP-, CGRP-, DBH- and TH-LI were present in the ganglia; some of these fibres being closely associated with the ganglion cells or with the cells showing TH-LI. The observation provide new information on the catecholamine-synthetic enzyme/neuropeptide expression of the ganglion and catecholamine-containing cells and of the associated nerve fibres of rat heart subepicardial ganglia.
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