ArticleAntimicrobial agents and chemotherapy2006
In vitro killing of nosocomial pathogens by acid and acidified nitrite.
Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- A nitrite-responsive regulatory RNA locus sustains commensal resilience against nitrosative stress.bioRxiv : the preprint server for biology · 2026Article
- Hydrochloric Acid Lock Therapy for Catheter-Related Bloodstream Infections: In Vitro Antimicrobial Activity and Catheter Material Compatibility.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Natural and induced immune responses in oral cavity and saliva.BMC immunology · 2025Review
- Gut Microbiota Composition Associated withPathogens (Basel, Switzerland) · 2022Review
- Article
- Achieving Partial Nitritation by Treating Sludge With Free Nitrous Acid: The Potential Role of Quorum Sensing.Frontiers in microbiology · 2022Review
- Regularized S-Map Reveals Varying Bacterial Interactions.Applied and environmental microbiology · 2020Article
- Fate of Methicillin-resistantFood science & nutrition · 2020Article
- Review
- Vancomycin-ResistantOpen forum infectious diseases · 2019Article
- Review
- The Intersection Between Colonization Resistance, Antimicrobial Stewardship, and Clostridium difficile.Current infectious disease reports · 2018Review
- Acid-Suppressive Therapy and Risk of Infections: Pros and Cons.Clinical drug investigation · 2017Review
- Clostridium difficile Infection and Fecal Microbiota Transplant.AACN advanced critical care · 2016Review
- Bacterial overgrowth and diversification of microbiota in gastric cancer.European journal of gastroenterology & hepatology · 2016Article
- Causes, Burden, and Prevention ofInfectious diseases in clinical practice (Baltimore, Md.) · 2015Article
- Article
- Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2015Review
- The impact of proton pump inhibitors on the human gastrointestinal microbiome.Clinics in laboratory medicine · 2014Review
- Clostridium difficile infection: management strategies for a difficult disease.Therapeutic advances in gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to pH 1 or 2 buffers or acidic gastric contents resulted in the killing of vancomycin-resistant Enterococcus sp., Klebsiella pneumoniae, Staphylococcus aureus, and Candida glabrata but not Clostridium difficile spores. Nitrite enhanced killing under acidic conditions, but significant killing of C. difficile spores required nitrite concentrations above usual physiological levels.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.