ArticleJournal of clinical microbiology2007
Diagnosis of human metapneumovirus infection in immunosuppressed lung transplant recipients and children evaluated for pertussis.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- A Mini-Review of Adverse Lung Transplant Outcomes Associated With Respiratory Viruses.Frontiers in immunology · 2019Pooled it
- The impact of the COVID-19 pandemic on other respiratory viruses in the Haut-Ogooué Province of Gabon.IJID regions · 2025Article
- Prevalence of Respiratory Pathogens in Nasopharyngeal Swabs of Febrile Patients with or without Respiratory Symptoms in the Niakhar Area of Rural Senegal.Pathogens (Basel, Switzerland) · 2024Article
- Genetic Diversity and Detection of Respiratory Viruses Excluding SARS-CoV-2 during the COVID-19 Pandemic in Gabon, 2020-2021.Viruses · 2024Article
- Advances in laboratory assays for detecting human metapneumovirus.Annals of translational medicine · 2020Review
- A multiplex one-tube nested real time RT-PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus.Virology journal · 2018Article
- Similar virus spectra and seasonality in paediatric patients with acute respiratory disease, Ghana and Germany.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2016Article
- Respiratory metapneumoviral infection without co-infection in association with acute and chronic lung allograft dysfunction.Journal of inflammation research · 2015Article
- Improving influenza surveillance in Portuguese preschool children by parents' report.European journal of pediatrics · 2014Article
- Viral etiology and seasonality of influenza-like illness in Gabon, March 2010 to June 2011.BMC infectious diseases · 2014Article
- Alternative molecular tests for virological diagnosis.Molecular biotechnology · 2013Review
- Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Real-time reverse transcriptase PCR assay for improved detection of human metapneumovirus.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2012Article
- Evaluation of the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait.Diagnostic microbiology and infectious disease · 2012Article
- Isolation of influenza viruses in MDCK 33016PF cells and clearance of contaminating respiratory viruses.Vaccine · 2012Article
- Clinical evaluation of multiplex real-time PCR panels for rapid detection of respiratory viral infections.Journal of medical virology · 2012Article
- Recombinant expression and immunological characterisation of proteins derived from human metapneumovirus.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2011Article
- Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients.Current opinion in infectious diseases · 2011Review
- Respiratory viruses in lung transplant recipients: a critical review and pooled analysis of clinical studies.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2011Review
- [Children with cancer and respiratory viral infection: epidemiology, diagnosis and treatment options].Enfermedades infecciosas y microbiologia clinica · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Human metapneumovirus (hMPV) is a recently discovered paramyxovirus that is known to cause respiratory tract infections in children and immunocompromised individuals. Given the difficulties of identifying hMPV by conventional culture, molecular techniques could improve the detection of this virus in clinical specimens. In this study, we developed a real-time reverse transcription-PCR (RT-PCR) assay designed to detect the four genetic lineages of hMPV. This assay and a commercial real-time nucleic acid sequence-based amplification (NASBA) assay (bioMérieux, Durham, NC) were used to determine the prevalence of hMPV in 114 immunosuppressed asymptomatic and symptomatic lung transplant recipients and 232 pediatric patients who were being evaluated for pertussis. hMPV was detected in 4.3% of the immunosuppressed lung transplant recipients and in 9.9% of children evaluated for pertussis. Both RT-PCR and NASBA assays were efficient in detection of hMPV infection in respiratory specimens. Even though hMPV was detected in a small number of the lung transplant recipients, it was still the most prevalent etiologic agent detected in patients with respiratory symptoms. In both of these diverse patient populations, hMPV infection was the most frequent viral respiratory tract infection identified. Given our findings, infection with hMPV infection should be determined as part of the differential diagnosis of respiratory illnesses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.