ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2007
Candidate gene identification of an aluminum-activated organic acid transporter gene at the Alt4 locus for aluminum tolerance in rye (Secale cereale L.).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed, 105 citations in OpenAlex.
- DNA Methylation Changes Reflect Aluminum Stress in Triticale and Epigenetic Control of the Trait.International journal of molecular sciences · 2025Article
- Genome wide identification of MATE and ALMT gene family in lentil (Lens culinaris Medikus) and expression profiling under Al stress condition.BMC plant biology · 2025Article
- Identification and Analysis of Aluminum-Activated Malate Transporter Gene Family Reveals Functional Diversification in Orchidaceae and the Expression Patterns ofInternational journal of molecular sciences · 2024Article
- Aluminum Stress Induces Irreversible Proteomic Changes in the Roots of the Sensitive but Not the Tolerant Genotype of Triticale Seedlings.Plants (Basel, Switzerland) · 2022Article
- Article
- Repression of Mitochondrial Citrate Synthase Genes by Aluminum Stress in Roots ofFrontiers in plant science · 2022Article
- Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis.Cell research · 2022Article
- Morpho-physiological characterization coupled with expressional accord of exclusion mechanism in wild and cultivated lentil under aluminum stress.Protoplasma · 2021Article
- Comprehensive characterization of the3 Biotech · 2020Article
- Heterologous Expression of aInternational journal of molecular sciences · 2020Article
- Assessing How the Aluminum-Resistance Traits in Wheat and Rye Transfer to Hexaploid and Octoploid Triticale.Frontiers in plant science · 2018Article
- Molecular markers associated with aluminium tolerance inHereditas · 2018Article
- The varied functions of aluminium-activated malate transporters-much more than aluminium resistance.Biochemical Society transactions · 2016Review
- Alteration of wheat vernalization requirement by alien chromosome-mediated transposition of MITE.Breeding science · 2016Article
- Quantitative Trait Loci and Inter-Organ Partitioning for Essential Metal and Toxic Analogue Accumulation in Barley.PloS one · 2016Article
- Oxidative Metabolism of Rye (Secale cereale L.) after Short Term Exposure to Aluminum: Uncovering the Glutathione-Ascorbate Redox Network.Frontiers in plant science · 2016Article
- Genetic mapping of a 7R Al tolerance QTL in triticale (x Triticosecale Wittmack).Journal of applied genetics · 2014Article
- Enhancement of aluminum tolerance in wheat by addition of chromosomes from the wild relative Leymus racemosus.Breeding science · 2013Article
- Roles of organic acid anion secretion in aluminium tolerance of higher plants.BioMed research international · 2013Review
- Aluminum tolerance association mapping in triticale.BMC genomics · 2012Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among cereal crops, rye is one of the most tolerant species to aluminum. A candidate gene approach was used to determine the likely molecular identity of an Al tolerance locus (Alt4). Using PCR primers designed from a wheat aluminum tolerance gene encoding an aluminum-activated malate transporter (TaALMT1), a rye gene (ScALMT1) was amplified, cloned and sequenced. Subsequently, the ScALMT1 gene of rye was found to be located on 7RS by PCR amplification using the wheat-rye addition lines. SNP polymorphisms for this gene were detected among the parents of three F(2) populations that segregate for the Alt4 locus. A map of the rye chromosome 7R, including the Alt4 locus ScALMT1 and several molecular markers, was constructed showing a complete co-segregation between Alt4 and ScALMT1. Furthermore, expression experiments were carried out to clarify the function of this candidate gene. Briefly, the ScALMT1 gene was found to be primarily expressed in the root apex and upregulated when aluminum was present in the medium. Five-fold differences in the expression were found between the Al tolerant and the Al non-tolerant genotypes. Additionally, much higher expression was detected in the rye genotypes than the moderately tolerant "Chinese Spring" wheat cultivar. These results suggest that the Alt4 locus encodes an aluminum-activated organic acid transporter gene that could be utilized to increase Al tolerance in Al sensitive plant species. Finally, TaALMT1 homologous sequences were identified in different grasses and in the dicotyledonous plant Phaseolus vulgaris. Our data support the hypothesis of the existence of a common mechanism of Al tolerance encoded by a gene located in the homoeologous group four of cereals.
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