Evidence map›Paper›PMID 17063186›Full record

ReviewNature reviews. Immunology2006

Dendritic-cell interactions with HIV: infection and viral dissemination.

Li Wu, Vineet N KewalRamani

Abstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 305 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
305citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

305 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. HIV Genome-Wide Protein Associations: a Review of 30 Years of Research.Microbiology and molecular biology reviews : MMBR · 2016
    Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Human CD123Journal of virus eradication · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Innate Immune Response to Viral Infection.Advances in experimental medicine and biology · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Sustained antiviral response againstFrontiers in pharmacology · 2024
    Article
  19. The role of dendritic cells in COVID-19 infection.Emerging microbes & infections · 2023
    Review
  20. Article

245 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Li WuDepartment of Microbiology and Molecular Genetics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA. liwu@mcw.edu
Vineet N KewalRamani

Funding

Mechanisms Underlying Dendritic Cell-mediated HIV TransmissionR01AI068493 · NIAID · OHIO STATE UNIVERSITY · PI WU, LI · 2006 to 2010
$1.5M
Intramural NIH HHSNIAID NIH HHS R01 AI068493
6 · The paper itself

Abstract

Dendritic cells (DCs) are crucial for the generation and the regulation of adaptive immunity. Because DCs have a pivotal role in marshalling immune responses, HIV has evolved ways to exploit DCs, thereby facilitating viral dissemination and allowing evasion of antiviral immunity. Defining the mechanisms that underlie cell-cell transmission of HIV and understanding the role of DCs in this process should help us in the fight against HIV infection. This Review highlights the latest advances in our understanding of the interactions between DCs and HIV, focusing on the mechanisms of DC-mediated viral dissemination.

Indexed as

CD4-Positive T-LymphocytesCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinDendritic CellsHIVHIV InfectionsHumansLectins, C-TypeReceptors, Cell SurfaceVirus InternalizationCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypeReceptors, Cell Surface

Identifiers

PMID17063186
PMCPMC1796806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.