ArticleJournal of human genetics2007
ADAM33 polymorphisms are associated with aspirin-intolerant asthma in the Japanese population.
Article in Journal of human genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Role of theInternational journal of molecular sciences · 2025Article
- Polymorphism in ADAM33 gene associated with asthmatics in West Bengal, India - An investigation by in-silico analysis.The World Allergy Organization journal · 2023Article
- Association analysis of ILVBL gene polymorphisms with aspirin-exacerbated respiratory disease in asthma.BMC pulmonary medicine · 2017Article
- Article
- Does aspirin-induced oxidative stress cause asthma exacerbation?Archives of medical science : AMS · 2015Article
- Association of a disintegrin and metalloprotease 33 gene polymorphisms with asthma.Molecular and clinical oncology · 2014Article
- Exonic variants associated with development of aspirin exacerbated respiratory diseases.PloS one · 2014Article
- Unraveling the genetic basis of aspirin hypersensitivity in asthma beyond arachidonate pathways.Allergy, asthma & immunology research · 2013Review
- Association of ADAM33 gene with susceptibility to COPD in Tibetan population of China.Molecular biology reports · 2011Article
- Association of ADAM33 gene polymorphisms with adult-onset asthma and its severity in an Indian adult population.Journal of genetics · 2011Article
- A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma.Immunogenetics · 2011Article
- Article
- Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.BMC pulmonary medicine · 2010Article
- Role of ADAM and ADAMTS metalloproteinases in airway diseases.Respiratory research · 2009Review
- Association of ADAM33 gene polymorphisms with adult concomitant allergic rhinitis and asthma in Chinese Han population.Molecular biology reports · 2009Article
- Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.BMC medical genetics · 2008Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple single nucleotide polymorphisms (SNPs) within ADAM33 have been reported to be associated with asthma and bronchial hyper-responsiveness in Caucasian populations. We examined whether these SNPs contribute to a predisposition to asthma, especially aspirin-intolerant asthma (AIA), in the Japanese population. Ten polymorphic sites (ST+4, ST+7, T1, T2, T+1, V-3, V-2, V-1, V4, V5) were genotyped in 102 AIA patients, 282 aspirin-tolerant asthma (ATA) patients and 120 control (CTR) subjects by direct sequencing. Haplotype frequencies were estimated by the expectation-maximization method. Differences in allele and haplotype frequencies among phenotypes were analyzed by the chi-square and permutation tests. ST+7, V-1 and V5 sites in the AIA group were significantly different from those in the ATA group (P=0.034-0.004) and from those in the CTR group (P=0.019-0.002). Haplotypes at three sites (ST+7, V-1, and V5) were significantly different in frequency between the AIA and ATA (P=0.008) or CTR (P=0.001) groups. Sequence variations in ADAM33 are likely to correlate with susceptibility to AIA in the Japanese population.
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