Evidence map›Paper›PMID 17060519›Full record

ArticleAntimicrobial agents and chemotherapy2007

In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.

R A Larsen, M Bauer, A E Brouwer, A Sanchez, A M Thomas, A Rajanuwong, W Chierakul, S J Peacock, N Day, N J White and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Antifungal Resistance in Cryptococcal Infections.Pathogens (Basel, Switzerland) · 2024
    Review
  2. Physiological Differences in Cryptococcus neoformans StrainsAntimicrobial agents and chemotherapy · 2017
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

R A LarsenDepartment of Medicine (Infectious Diseases), 2020 Zonal Ave., IRD Room 620, MC 9520, University of Southern California, Los Angeles, CA 90033, USA. rlarsen@usc.edu
M Bauer
A E Brouwer
A Sanchez
A M Thomas
A Rajanuwong
W Chierakul
S J Peacock
N Day
N J White
M G Rinaldi
T S Harrison
Mahidol University · THUniversity of Southern California · USMahidol Oxford Tropical Medicine Research Unit · THSappasithiprasong Hospital · THSt George's Hospital · GBThe University of Texas Health Science Center at San Antonio · USUniversity of Northern Colorado · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Reliable measures of antifungal drug susceptibility are needed. We tested the susceptibility of Cryptococcus neoformans from patients treated with amphotericin B. In vitro susceptibility employed a modified broth macrodilution method. We demonstrate a strong correlation between the quantitative measures of in vitro amphotericin B susceptibility and the quantitative response observed in patients.

Indexed as

AIDS-Related Opportunistic InfectionsAmphotericin BAntifungal AgentsCryptococcus neoformansHumansMeningitis, CryptococcalMicrobial Sensitivity TestsRegression AnalysisAmphotericin BAntifungal Agents

Identifiers

PMID17060519
PMCPMC1797648
OpenAlexW2107350902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.