ArticleJournal of bacteriology2007
Response of Staphylococcus aureus to salicylate challenge.
Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Transcriptomic and Metabolomic Analysis of a Fusidic Acid-SelectedAntibiotics (Basel, Switzerland) · 2022Article
- Role of sodium salicylate inFrontiers in microbiology · 2022Article
- Non-antibiotic pharmaceuticals promote the transmission of multidrug resistance plasmids through intra- and intergenera conjugation.The ISME journal · 2021Article
- Microbiology of the American Smokeless Tobacco.Applied microbiology and biotechnology · 2021Review
- Article
- Nonsteroidal antiinflammatory drugs alter antibiotic susceptibility and expression of virulence-related genes and protein A of Staphylococcus aureusTurkish journal of medical sciences · 2021Article
- Salicylic acid stabilizes Staphylococcus aureus biofilm by impairing the agr quorum-sensing system.Scientific reports · 2021Article
- In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria.Scientific reports · 2019Article
- The Polycyclic Polyprenylated Acylphloroglucinol Antibiotic PPAP 23 Targets the Membrane and Iron Metabolism inFrontiers in microbiology · 2019Article
- Complex gene response of herbicide-resistant3 Biotech · 2018Article
- Salicylic Acid Reduces OmpF Expression, RenderingChonnam medical journal · 2018Article
- The isolation of Staphylococcus aureus tea tree oil-reduced susceptibility mutants.Phytotherapy research : PTR · 2014Article
- Tea tree oil-induced transcriptional alterations in Staphylococcus aureus.Phytotherapy research : PTR · 2013Article
- Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.Chemistry & biology · 2011Article
- Alterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac.Annals of clinical microbiology and antimicrobials · 2011Article
- Transcriptome analysis of alkali shock and alkali adaptation in Listeria monocytogenes 10403S.Foodborne pathogens and disease · 2010Article
- Salicylic acid diminishes Staphylococcus aureus capsular polysaccharide type 5 expression.Infection and immunity · 2010Article
- Review
- sarA inactivation reduces vancomycin-intermediate and ciprofloxacin resistance expression by Staphylococcus aureus.International journal of antimicrobial agents · 2009Article
- A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.Molecular microbiology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Growth of Staphylococcus aureus with the nonsteroidal anti-inflammatory salicylate reduces susceptibility of the organism to multiple antimicrobials. Transcriptome analysis revealed that growth of S. aureus with salicylate leads to the induction of genes involved with gluconate and formate metabolism and represses genes required for gluconeogenesis and glycolysis. In addition, salicylate induction upregulates two antibiotic target genes and downregulates a multidrug efflux pump gene repressor (mgrA) and sarR, which represses a gene (sarA) important for intrinsic antimicrobial resistance. We hypothesize that these salicylate-induced alterations jointly represent a unique mechanism that allows S. aureus to resist antimicrobial stress and toxicity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.