Trial reportBMJ (Clinical research ed.)2006
Effectiveness of community physiotherapy and enhanced pharmacy review for knee pain in people aged over 55 presenting to primary care: pragmatic randomised trial.
Trial report in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05173064 (Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist), which is not on this map. Cited by 66 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist (TSP) Dedicated to Quality Enhancement and Cost Reduction in Knee Osteoarthritis Exercise Rehabilitation
Who cites it
66 citing papers in PubMed, 12 syntheses or guidelines pooled it, 172 citations in OpenAlex.
- Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024Pooled it
- A recommended exercise program appropriate for patients with knee osteoarthritis: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- The Time Course of Quadriceps Strength Recovery After Total Knee Arthroplasty Is Influenced by Body Mass Index, Sex, and Age of Patients: Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Neurostructural correlates of strength decrease following total knee arthroplasty: A systematic review of the literature with meta-analysis.Bosnian journal of basic medical sciences · 2020Pooled it
- Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Pooled it
- Evidence synthesis of types and intensity of therapeutic land-based exercises to reduce pain in individuals with knee osteoarthritis.Rheumatology international · 2019Pooled it
- Pharmacist services for non-hospitalised patients.The Cochrane database of systematic reviews · 2018Pooled it
- Effectiveness of Models Used to Deliver Multimodal Care for Chronic Musculoskeletal Pain: a Rapid Evidence Review.Journal of general internal medicine · 2018Pooled it
- Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review.The Cochrane database of systematic reviews · 2018Pooled it
- Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2015Pooled it
- Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis.BMJ (Clinical research ed.) · 2013Pooled it
- Effect of outpatient pharmacists' non-dispensing roles on patient outcomes and prescribing patterns.The Cochrane database of systematic reviews · 2010Pooled it
- Medication review improves pain management and quality of life in chronic pain: a pilot randomized controlled study.Scientific reports · 2025Trial
- Impact of Monthly Community Follow-Ups in Knee Osteoarthritis Management for Elderly Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Arthroscopic hip surgery compared with personalised hip therapy in people over 16 years old with femoroacetabular impingement syndrome: UK FASHIoN RCT.Health technology assessment (Winchester, England) · 2022Trial
- Low adherence to exercise may have influenced the proportion of OMERACT-OARSI responders in an integrated osteoarthritis care model: secondary analyses from a cluster-randomised stepped-wedge trial.BMC musculoskeletal disorders · 2020Trial
- Periosteal Electrical Dry Needling as an Adjunct to Exercise and Manual Therapy for Knee Osteoarthritis: A Multicenter Randomized Clinical Trial.The Clinical journal of pain · 2018Trial
- Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial.Lancet (London, England) · 2018Trial
- Impairment-targeted exercises for older adults with knee pain: a proof-of-principle study (TargET-Knee-Pain).BMC musculoskeletal disorders · 2016Trial
- Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial.Annals of the rheumatic diseases · 2015Trial
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effectiveness of two primary care strategies for delivering evidence based care to people aged 55 or over with knee pain: enhanced pharmacy review and community physiotherapy.
designPragmatic multicentre randomised clinical trial.
setting15 general practices in North Staffordshire.
participants325 adults aged 55 years or over (mean 68 years) consulting with knee pain; 297 (91%) reached six month follow-up.
interventionsEnhanced pharmacy review (pharmacological management in accordance with an algorithm); community physiotherapy (advice about activity and pacing and an individualised exercise programme); control (advice leaflet reinforced by telephone call).
main outcome measureChange in Western Ontario and McMaster Universities osteoarthritis index (WOMAC) at 3, 6, and 12 months.
resultsMean baseline WOMAC pain score was 9.1 (SD 3.7), and mean baseline function score was 29.9 (SD 12.8). At three months, the mean reductions in pain scores were 0.41 (SD 2.8) for control, 1.59 (3.2) for pharmacy, and 1.56 (3.4) for physiotherapy; reductions in function scores were 0.80 (8.5), 2.61 (9.8), and 4.79 (10.8). Compared with control, mean differences in change scores for physiotherapy were 1.15 (95% confidence interval 0.2 to 2.1) for pain and 3.99 (1.2 to 6.8) for function; those for pharmacy were 1.18 (0.3 to 2.1) for pain and 1.80 (-0.8 to 4.5) for function. These differences were not sustained to six or 12 months. Significantly fewer participants in the physiotherapy group reported consulting their general practitioner for knee pain in the follow-up period, and use of non-steroidal anti-inflammatory drugs was lower in the physiotherapy and pharmacy groups than in the control group.
conclusionsEvidence based care for older adults with knee pain, delivered by primary care physiotherapists and pharmacists, resulted in short term improvements in health outcomes, reduced use of non-steroidal anti-inflammatory drugs, and high patient satisfaction. Physiotherapy seemed to produce a shift in consultation behaviour away from the traditional general practitioner led model of care.
trial registrationUK National Research Register N0286046917; Current Controlled Trials ISRCTN55376150 [controlled-trials.com] .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.