Evidence map›Paper›PMID 17055773›Full record

ReviewCurrent opinion in microbiology2006

Morphogenesis and cell cycle progression in Candida albicans.

Judith Berman

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 247 citations in OpenAlex.

  1. Article
  2. Article
  3. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  4. Article
  5. Article
  6. The Macroevolution of Filamentation Morphology Across thebioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Review
  9. Overcoming antifungal resistance inFrontiers in cellular and infection microbiology · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Physiological adventures inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  16. eLife · 2023
    Article
  17. Cell Cycle Analysis ofBio-protocol · 2023
    Article
  18. Newly Discovered Antimicrobial Peptide ScyampcinAntimicrobial agents and chemotherapy · 2023
    Article
  19. Review
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Judith BermanDepartment of Genetics, Cell Biology and Development, 6-160 Jackson Hall, 321 Church Street SE, University of Minnesota, Minneapolis, MN 55455, USA. jberman@umn.edu
University of Minnesota · US

Funding

ZDS2P REGULATES SWE1P-DEPENDENT POLARIZED CELL GROWTH IN S CEREVISIAEP41RR011823 · NCRR · UNIVERSITY OF WASHINGTON · PI DAVIS, TRACY · 1996 to 2011
$24.7M
Morphogenesis and Cell Cycle Regulation in C. albicansR01DE014666 · NIDCR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERMAN, JUDITH G. · 2002 to 2006
$1.8M
NCRR NIH HHS P41 RR011823NIAID NIH HHS R01 AI/DE14666NIDCR NIH HHS R01 DE014666
6 · The paper itself

Abstract

Candida albicans, an opportunistic human pathogen, displays three modes of growth: yeast, pseudohyphae and true hyphae, all of which differ both in morphology and in aspects of cell cycle progression. In particular, in hyphal cells, polarized growth becomes uncoupled from other cell cycle events. Yeast or pseudohyphae that undergo a cell cycle delay also exhibit polarized growth, independent of cell cycle progression. The Spitzenkörper, an organelle composed of vesicles associated with hyphal tips, directs continuous hyphal elongation in filamentous fungal species and also in C. albicans hyphae. A polarisome mediates cell cycle dependent growth in yeast and pseudohyphae. Regulation of morphogenesis and cell cycle progression is dependent upon specific cyclins, all of which affect morphogenesis and some of which function specifically in yeast or hyphal cells. Future work will probably focus on the cell cycle checkpoints involved in connecting morphogenesis to cell cycle progression.

Indexed as

Candida albicansCell CycleCell Cycle ProteinsCell PolarityGene Expression Regulation, FungalHyphaeMorphogenesisProtein KinasesCell Cycle ProteinsProtein Kinases

Identifiers

PMID17055773
PMCPMC3552184
OpenAlexW2135741099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.