ArticleJournal of mammary gland biology and neoplasia2006
Computed tomography for imaging the breast.
Article in Journal of mammary gland biology and neoplasia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 147 citations in OpenAlex.
- A Droplet-Microarray Platform for Multiplex Profiling of Breast Cancer Exosome Subtypes in Patients' Blood Plasma Samples.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Imaging and Diagnostic Tools for Cetacean Mammary Gland Assessment: Challenges and Future Directions for Marine Mammal Pathology, Medicine and Research.Journal of mammary gland biology and neoplasia · 2025Review
- Emerging nanoparticle-based x-ray imaging contrast agents for breast cancer screening.Nanomedicine (London, England) · 2025Review
- New progress in imaging diagnosis and immunotherapy of breast cancer.Frontiers in immunology · 2025Review
- Model-Based 3-D X-Ray Induced Acoustic Computerized Tomography.IEEE transactions on radiation and plasma medical sciences · 2023Article
- Modern Imaging Techniques in the Study and Disease Diagnosis of the Mammary Glands of Animals.Veterinary sciences · 2023Review
- Dedicated breast CT: state of the art-Part II. Clinical application and future outlook.European radiology · 2022Review
- Model-Based X-Ray-Induced Acoustic Computed Tomography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Dose and spatial resolution analysis of grating-based phase-contrast mammography using an inverse Compton x-ray source.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- First-in-Human Study of Acoustic Angiography in the Breast and Peripheral Vasculature.Ultrasound in medicine & biology · 2017Article
- Initial Experience with a Cone-beam Breast Computed Tomography-guided Biopsy System.Journal of clinical imaging science · 2017Article
- High-resolution (18)F-FDG PET/CT for assessing disease activity in rheumatoid and psoriatic arthritis: findings of a prospective pilot study.The British journal of radiology · 2016Article
- Article
- Population of 224 realistic human subject-based computational breast phantoms.Medical physics · 2016Article
- Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT.Medical physics · 2015Article
- Optical measurement of dimensional parameters of the breast with subjects in prone position.Journal of medical imaging (Bellingham, Wash.) · 2015Article
- The potential of L-shell X-ray fluorescence CT (XFCT) for molecular imaging.The British journal of radiology · 2015Review
- High-resolution 3D micro-CT imaging of breast microcalcifications: a preliminary analysis.BMC cancer · 2014Article
- Bioelectrical Impedance Methods for Noninvasive Health Monitoring: A Review.Journal of medical engineering · 2014Review
- Measurement of breast tissue composition with dual energy cone-beam computed tomography: a postmortem study.Medical physics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Despite the success of screening mammography contributing to the reduction of cancer mortality, a number of other imaging techniques are being studied for breast cancer screening. In our laboratory, a dedicated breast computed tomography (CT) system has been developed and is currently undergoing patient testing. The breast CT system is capable of scanning the breast with the woman lying prone on a tabletop, with the breast in the pendant position. A 360 degrees scan currently requires 16.6 s, and a second scanner with a 9-second scan time is nearly operational. Extensive effort was placed on computing the radiation dose to the breast under CT geometry, and the scan parameters are selected to utilize the same radiation dose levels as two-view mammography. A total of 55 women have been scanned, ten healthy volunteers in a Phase I trial, and 45 women with a high likelihood of having breast cancer in a Phase II trial. The breast CT process leads to the production of approximately three hundred 512 x 512 images for each breast. Subjective evaluation of the breast CT images reveals excellent anatomical detail, good depiction of microcalcifications, and exquisite visualization of the soft tissue components of the tumor when contrasted against adipose tissues. The use of iodine contrast injection dramatically enhances the visualization of tumors. While a thorough scientific investigation based upon observer performance studies is in progress, initial breast CT images do appear promising and it is likely that breast CT will play some role in breast cancer imaging.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.