ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Neuromechanics of multifunctionality during rejection in Aplysia californica.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Motor priming is associated with widespread recruitment into neural ensembles and more rapid ensemble transitions.iScience · 2026Article
- Context-dependent mechanical reconfiguration is necessary for multifunctional behavior in an intrinsically confined hydrostat.iScience · 2026Article
- NEURONpyxl: fast, flexible, Python-integrated simulation of biophysical neural networks with complex plastic synapses.Frontiers in computational neuroscience · 2026Article
- Article
- Incorporating buccal mass planar mechanics and anatomical features improves neuromechanical modeling of Aplysia feeding behavior.Biological cybernetics · 2025Article
- Identified neurons B4/B5 function as sensory neurons, motor neurons, and interneurons inJournal of neurophysiology · 2025Article
- A computational neural model that incorporates both intrinsic dynamics and sensory feedback in the Aplysia feeding network.Biological cybernetics · 2024Article
- Multiple changes in connectivity between buccal ganglia mechanoafferents and motor neurons with different functions after learning that food is inedible inLearning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Repeated stimulation of feeding mechanoafferents inLearning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Cellular mechanisms underlying carry-over effects after magnetic stimulation.Scientific reports · 2024Article
- Variable task switching in the feeding network ofJournal of neurophysiology · 2023Article
- Variational and phase response analysis for limit cycles with hard boundaries, with applications to neuromechanical control problems.Biological cybernetics · 2022Article
- Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation.Scientific reports · 2022Article
- Somatic inhibition by microscopic magnetic stimulation.Scientific reports · 2021Article
- Dynamical consequences of sensory feedback in a half-center oscillator coupled to a simple motor system.Biological cybernetics · 2021Article
- Control for multifunctionality: bioinspired control based on feeding in Aplysia californica.Biological cybernetics · 2020Article
- Axonal blockage with microscopic magnetic stimulation.Scientific reports · 2020Article
- Multiple Local Synaptic Modifications at Specific Sensorimotor Connections after Learning Are Associated with Behavioral Adaptations That Are Components of a Global Response Change.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Precise timing is ubiquitous, consistent, and coordinated across a comprehensive, spike-resolved flight motor program.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Successful and unsuccessful attempts to swallow in a reducedLearning & memory (Cold Spring Harbor, N.Y.) · 2019Article
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Authors and funding
3 authors.
Funding
Abstract
How are the same muscles and neurons used to generate qualitatively different behaviors? We studied this question by analyzing the biomechanical and neural mechanisms of rejection responses in the marine mollusk Aplysia californica and compared these mechanisms with those used to generate swallowing responses (Ye et al., 2006). During rejection, the central grasper of the feeding structure closes to push inedible food out of the buccal cavity. This contrasts with swallowing, during which the grasper is open as it moves toward the jaws (protracts). We examined how the shape change of the grasper during rejection mechanically reconfigured the surrounding musculature. Grasper shape change increased the effectiveness of protractor muscle I2. The closed grasper alters the function of another muscle, the hinge, which becomes capable of inducing ventral rotations of rejected material. In contrast, during large-amplitude swallows, the hinge muscle mediates dorsal rotations of ingested material. Finally, after the grasper opens, its change in shape induces a delay in the activation of other surrounding muscles, the I1/I3/jaw complex, whose premature activation would close the halves of the grasper and induce it to pull inedible material back inward. The delay in activation of the I1/I3/jaw complex is partially attributable to identified multiaction neurons B4/B5. The results suggest that multifunctionality emerges from a periphery in which flexible coalitions of muscles may perform different functions in different mechanical contexts and in which neural circuitry is capable of reorganizing to exploit these coalitions by changes in phasing, duration, and intensity of motor neuronal activation.
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