ArticleMolecular and cellular neurosciences2006
Expression of classical cadherins in the cerebellar anlage: quantitative and functional aspects.
Article in Molecular and cellular neurosciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Revisiting the development of cerebellar inhibitory interneurons in the light of single-cell genetic analyses.Histochemistry and cell biology · 2024Review
- Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells.International journal of molecular sciences · 2019Article
- N-cadherin provides aProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Moving into shape: cell migration during the development and histogenesis of the cerebellum.Histochemistry and cell biology · 2018Review
- The biomechanical properties of an epithelial tissue determine the location of its vasculature.Nature communications · 2016Article
- Cadherins in cerebellar development: translation of embryonic patterning into mature functional compartmentalization.Cerebellum (London, England) · 2011Review
- Article
- Laminar fate and phenotype specification of cerebellar GABAergic interneurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Besides Purkinje cells and granule neurons: an appraisal of the cell biology of the interneurons of the cerebellar cortex.Histochemistry and cell biology · 2008Review
- Development of cerebellar GABAergic interneurons: origin and shaping of the "minibrain" local connections.Cerebellum (London, England) · 2008Review
- Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.BMC developmental biology · 2007Article
- Prolonged glial expression of Sox4 in the CNS leads to architectural cerebellar defects and ataxia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
During central nervous system (CNS) development, cell migration precedes and is key to the integration of diverse sets of cells. Mechanistically, CNS histogenesis is realized through a balanced interplay of cell-cell and cell-matrix adhesion molecules. Here, we summarize experiments that probe the developmental expression and potential significance of a set of cadherins, including M-, N- and R-cadherin, for patterning of the cerebellar cortex. We established a transgenic marker that allows cerebellar granule cells to be followed from the neuroblast stage to their final, postmitotic settlement. In conjunction with flow cytometry, this allowed us to derive a quantitative view of cadherin expression in differentiating granule cells and relate it to the expression of the same cadherins in cerebellar inhibitory interneuronal precursors. In vitro reaggregation analysis supports a role for cadherins in cell sorting and migration within the nascent cerebellar cortex that may be rationalized within the context of the differential adhesion hypothesis (Foty, R.A. and Steinberg, M.S., 2005. The differential adhesion hypothesis: a direct evaluation. Dev. Biol. 278, 255-263.).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.