ArticleCell biophysics1990
Depletion flocculation and depletion stabilization of erythrocytes.
Article in Cell biophysics, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- The Impact of Biophysical Properties of Erythrocytes on their Aggregation.International journal of biomedical science : IJBS · 2017Article
- Microfluidic system for monitoring temporal variations of hemorheological properties and platelet adhesion in LPS-injected rats.Scientific reports · 2017Article
- Effect of diabetic duration on hemorheological properties and platelet aggregation in streptozotocin-induced diabetic rats.Scientific reports · 2016Article
- Microfluidic-based speckle analysis for sensitive measurement of erythrocyte aggregation: A comparison of four methods for detection of elevated erythrocyte aggregation in diabetic rat blood.Biomicrofluidics · 2015Article
- The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation.Biophysical journal · 2004Article
- Depletion-mediated red blood cell aggregation in polymer solutions.Biophysical journal · 2002Article
- Localized contact formation by erythrocyte membranes: electrostatic effects.Biophysical journal · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At dextran (Mw approximately 500,000) concentrations from 2 to approximately 10%, suspensions of normal human erythrocytes flocculate in small convex agglutinates. At dextran concentrations greater than 10%, the erythrocytes resegregate in a stable monodisperse suspension. At all these dextran concentrations, the erythrocytes are coated with considerable amounts of dextran. It can be argued that at dextran concentrations from 2 to 10%, as well as at dextran concentrations greater than 10%, there is a thin layer, which is depleted of dextran, between the dextran layer adsorbed onto the erythrocytes and the bulk dextran solution. It can also be shown that there is a repulsive interaction between the two layers of dextran: one adsorbed and one free. When the adsorbed dextran layer is the most concentrated, stability must ensue, and when the dextran in free solution is the most concentrated, flocculation should occur. Below 7% dextran, the concentration of free dextran is higher than the adsorbed concentration; above 10% dextran that situation is reversed. These data correlate well with the depletion flocculation predicted for the lower concentration and the depletion stabilization predicted for the higher dextran concentration.
Indexed as
Identifiers
1704813What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.