ArticleIntensive care medicine2006
Alveolar recruitment assessed by positron emission tomography during experimental acute lung injury.
Article in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
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- Imaging the acute respiratory distress syndrome: past, present and future.Intensive care medicine · 2022Review
- Imaging the Injured Lung: Mechanisms of Action and Clinical Use.Anesthesiology · 2019Review
- Positron emission tomography: a tool for better understanding of ventilator-induced and acute lung injury.Current opinion in critical care · 2011Review
- Measurement of regional specific lung volume change using respiratory-gated PET of inhaled 13N-nitrogen.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2010Article
- Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: an experimental study.Critical care (London, England) · 2009Article
- FDG-PET in patients at risk for acute respiratory distress syndrome: a preliminary report.Intensive care medicine · 2008Article
- Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal failure and endocrinology.Intensive care medicine · 2007Review
- Unveiling alveolar recruitment: the fascinating trail between theory and practice.Intensive care medicine · 2006Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare changes in aerated lung volumes measured by positron emission tomography (PET) and inflation volume-pressure curve (V-P) of the respiratory system, and to evaluate the reliability of PET to assess alveolar recruitment. DESIGN AND
settingExperimental study in six anesthetized and mechanically ventilated pigs in a PET facility in an experimental university laboratory.
interventionsLung injury was induced by oleic acid. Animals were randomly studied in four conditions: PEEP 0cmH(2)O (ZEEP) in supine position (SP), PEEP 10cmH(2)O in SP, ZEEP in prone position (PP) and PEEP in PP, each applied for 30min. MEASUREMENTS AND
resultsWith PET aerated lung volume was obtained from pulmonary density analysis using transmission scan (VA(trans)) and from nitrogen-13 kinetics on emission scan (VA(em)). Changes in VA(trans) and VA(em) were computed as the difference in aerated volume between conditions. VA(trans) and VA(em) did not differ between SP and PP, on either ZEEP or PEEP, suggesting no modification in relaxation volume of the respiratory system induced by posture. Changes in VA(trans) or VA(em) were significantly correlated with changes in aerated volume assessed from superimposed V-P curves (R (2)=0.74 and 0.75, respectively). Alveolar recruitment assessed by PET was significantly correlated with both PaO(2) (R (2)=0.61) and PaCO(2) (R (2)=0.40) variations induced by PEEP.
conclusionsPET is a new reliable tool of scientific interest to image lung volume and alveolar recruitment during acute lung injury.
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