ArticleArchives of oral biology2007
Physiological and serological variation in Streptococcus mitis biovar 1 from the human oral cavity during the first year of life.
Article in Archives of oral biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.Microbiome · 2024Article
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.bioRxiv : the preprint server for biology · 2024Article
- The Predominant Oral Microbiota Is Acquired Early in an Organized Pattern.Scientific reports · 2019Article
- The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells.International journal of oral science · 2017Article
- Effects of Pseudomonas aeruginosa and Streptococcus mitis mixed infection on TLR4-mediated immune response in acute pneumonia mouse model.BMC microbiology · 2017Article
- Commensal Streptococcus mitis is a unique vector for oral mucosal vaccination.Microbes and infection · 2015Article
- Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms.Journal of bacteriology · 2010Article
- Antibody binding to Streptococcus mitis and Streptococcus oralis cell fractions.Archives of oral biology · 2008Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveThe purpose of the study was to explore the physiological and antigenic diversity of a large number of Streptococcus mitis biovar 1 isolates in order to begin to determine whether these properties contribute to species persistence.
designS. mitis biovar 1 was collected from four infants from birth to the first year of age. At each of eight to nine visits, 60 isolates each were obtained from the cheeks, tongue and incisors (once erupted) yielding 4440 in total. These were tested for production of neuraminidase, beta1-N-acetylglucosaminidase, beta1-N-acetylgalactosaminidase, IgA1 protease and amylase-binding. Antigenic diversity was examined by ELISA and Western immunoblotting using antisera raised against S. mitis biovar 1 NCTC 12261(T) and SK145.
resultsThree thousand three hundred and thirty (75%) of the isolates were identified as S. mitis biovar 1 and 3144 (94.4%) could be divided into four large phenotypic groups based on glycosidase production. Fifty-four percent of the isolates produced IgA1 protease, but production was disproportionate among the phenotypes. Between one-third and one-half of the strains of each phenotype bound salivary alpha-amylase. Antisera against strains NCTC 12261(T) and SK145 displayed different patterns of reactivity with randomly selected representatives of the four phenotypes.
conclusionsS. mitis biovar 1 is physiologically and antigenically diverse, properties which could aid strains in avoiding host immunity and promote re-colonization of a habitat or transfer to a new habitat.
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