Evidence map›Paper›PMID 17043103›Full record

ArticleInfection and immunity2007

Protein P200 is dispensable for Mycoplasma pneumoniae hemadsorption but not gliding motility or colonization of differentiated bronchial epithelium.

Jarrat L Jordan, How-Yi Chang, Mitchell F Balish, Lynley S Holt, Stephanie R Bose, Benjamin M Hasselbring, Robert H Waldo, Thomas M Krunkosky, Duncan C Krause

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 58 citations in OpenAlex.

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  6. Behaviors and Energy Source ofJournal of bacteriology · 2019
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  10. Review
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  13. Article
  14. A Compendium for Mycoplasma pneumoniae.Frontiers in microbiology · 2016
    Review
  15. Article
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jarrat L JordanDepartment of Microbiology, University of Georgia, Athens, GA 30602, USA.
How-Yi Chang
Mitchell F Balish
Lynley S Holt
Stephanie R Bose
Benjamin M Hasselbring
Robert H Waldo
Thomas M Krunkosky
Duncan C Krause
University of Tennessee Health Science Center · USMiami University · USUniversity of Georgia · US

Funding

Mycoplasma pneumoniae Gliding MotilityR01AI049194 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI JENSEN, GRANT J, KRAUSE, DUNCAN C · 2002 to 2012
$2.7M
GENETIC ANALYSIS OF MYCOPLASMA PNEUMONIAE CELL ADHERENCER01AI023362 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI KRAUSE, DUNCAN C · 1986 to 2008
$2.4M
NIAID NIH HHS AI22362NIAID NIH HHS AI49194NIAID NIH HHS R01 AI023362NIAID NIH HHS R01 AI049194
6 · The paper itself

Abstract

Mycoplasma pneumoniae protein P200 was localized to the terminal organelle, which functions in cytadherence and gliding motility. The loss of P200 had no impact on binding to erythrocytes and A549 cells but resulted in impaired gliding motility and colonization of differentiated bronchial epithelium. Thus, gliding may be necessary to overcome mucociliary clearance.

Indexed as

Bacterial AdhesionBacterial ProteinsBase SequenceBlotting, WesternBronchiCell Line, TumorFluorescent Antibody TechniqueHemadsorptionHumansMembrane ProteinsMicroscopy, Electron, TransmissionMolecular Sequence DataMucociliary ClearanceMycoplasma pneumoniaePolymerase Chain ReactionRespiratory MucosaBacterial ProteinsMembrane ProteinsP200 protein, Mycoplasma pneumoniae

Identifiers

PMID17043103
PMCPMC1828431
OpenAlexW2152177550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.