ArticleMolecular genetics and genomics : MGG2006
The Bradyrhizobium japonicum Fur protein is an iron-responsive regulator in vivo.
Article in Molecular genetics and genomics : MGG, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Engineering rhizobial bioinoculants: a strategy to improve iron nutrition.TheScientificWorldJournal · 2013Review
- Bacterial outer membrane channel for divalent metal ion acquisition.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Transcriptional control of the Bradyrhizobium japonicum irr gene requires repression by fur and Antirepression by Irr.The Journal of biological chemistry · 2010Article
- The mntH gene encodes the major Mn(2+) transporter in Bradyrhizobium japonicum and is regulated by manganese via the Fur protein.Molecular microbiology · 2009Article
- Positive control of ferric siderophore receptor gene expression by the Irr protein in Bradyrhizobium japonicum.Journal of bacteriology · 2009Article
- Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteria.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2009Article
- Expression of hurP, a gene encoding a prospective site 2 protease, is essential for heme-dependent induction of bhuR in Bordetella bronchiseptica.Journal of bacteriology · 2007Article
- Genomes of the symbiotic nitrogen-fixing bacteria of legumes.Plant physiology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The Fur protein is a global regulator of iron metabolism in many bacterial species. However, Fur homologs from some rhizobia appear not to mediate iron-dependent gene expression in vivo. Here, transcriptional profiling analysis showed that more than one-fourth of the genes within the iron stimulon of Bradyrhizobium japonicum were aberrantly controlled by iron in a fur mutant. However, Fur has only a modest role in regulating iron transport genes. Quantitative real time reverse transcriptase PCR measurements confirmed abnormal gene expression in iron-limited cells of the fur strain, thereby demonstrating that Fur must function under those conditions. The findings show that B. japonicum Fur is involved in iron-dependent gene expression, and support the conclusion that rhizobial Fur proteins have novel functions compared with well studied model systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.