ReviewJournal of the American Geriatrics Society2006
Traumatic brain injury in older adults: epidemiology, outcomes, and future implications.
Review in Journal of the American Geriatrics Society, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 267 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
267 citing papers in PubMed, 6 syntheses or guidelines pooled it, 676 citations in OpenAlex.
- Functional recovery in older adults following mild traumatic brain injury: a systematic review.European geriatric medicine · 2026Pooled it
- The effectiveness of clinical frailty assessment in older patients with Traumatic brain injury in predicting outcome and quality of life: a systematic review.Neurosurgical review · 2025Pooled it
- Traumatic Brain Injury and Alzheimer's Disease Biomarkers: A Systematic Review of Findings from Amyloid and Tau Positron Emission Tomography.Journal of neurotrauma · 2025Pooled it
- Risk Factors for Fall-Related Mild Traumatic Brain Injuries Among Older Adults: A Systematic Review Highlighting Research Gaps.International journal of environmental research and public health · 2025Pooled it
- Long-term life expectancy in severe traumatic brain injury: a systematic review.European journal of physical and rehabilitation medicine · 2024Pooled it
- Comorbidity in adults with traumatic brain injury and all-cause mortality: a systematic review.BMJ open · 2019Pooled it
- Trial
- Safety and efficacy of Cerebrolysin in acute brain injury and neurorecovery: CAPTAIN I-a randomized, placebo-controlled, double-blind, Asian-Pacific trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Trial
- Moderate and Severe Traumatic Brain Injury Outcomes-A 20 Year (2002-2021) Analysis.Emergency medicine Australasia : EMA · 2026Article
- Early and safer triage in elderly traumatic brain injury using a portable NIRS - based device: clinical evaluation of CEREBOEmergency radiology · 2026Article
- Andexanet alfa Reduces Hematoma Expansion Following Controlled Cortical Impact in Mice Pretreated with Rivaroxaban.Neurocritical care · 2026Article
- EEG-based assessment of sustained attention in geriatric inpatients: a feasibility study.GeroScience · 2026Article
- Epidemiology of spinal cord injury in the context of closed head injury.The journal of spinal cord medicine · 2026Article
- A nomogram for the prediction of traumatic intracranial abnormalities in the elderly: Development and validation.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- 6-Month Recovery after Mild Traumatic Brain Injury in Older Adults: A TRACK-GERI Study.medRxiv : the preprint server for health sciences · 2026Article
- Substance Use and Traumatic Brain Injury: Evidence from a Rural Trauma Center.International journal of environmental research and public health · 2026Observational
- Elderly at a Crossroads: Rehabilitation and Hospice Outcomes in Small Traumatic Brain Injuries.Clinical medicine & research · 2026Article
- ASA class is independently associated with 30-day mortality after mild traumatic brain injury with intracranial injury: a national retrospective cohort study.Acta neurochirurgica · 2026Article
- Diagnostic Accuracy of Plasma Biomarkers for Mild Traumatic Brain Injury in Older Adults.JAMA network open · 2026Article
- Epidemiology of Traumatic Brain Injury in Medicare Beneficiaries over the Last Decade: A Retrospective Observational Study.Health science reports · 2026Article
207 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Traumatic brain injury (TBI) is a significant problem in older adults. In persons aged 65 and older, TBI is responsible for more than 80,000 emergency department visits each year; three-quarters of these visits result in hospitalization as a result of the injury. Adults aged 75 and older have the highest rates of TBI-related hospitalization and death. Falls are the leading cause of TBI for older adults (51%), and motor vehicle traffic crashes are second (9%). Older age is known to negatively influence outcome after TBI. Although geriatric and neurotrauma investigators have identified the prognostic significance of preadmission functional ability, comorbidities, sex, and other factors such as cerebral perfusion pressure on recovery after illness or injury, these variables remain understudied in older adults with TBI. In the absence of good clinical data, predicting outcomes and providing care in the older adult population with TBI remains problematic. To address this significant public health issue, a refocusing of research efforts on this population is justified to prevent TBI in the older adult and to discern unique care requirements to facilitate best patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.