Evidence map›Paper›PMID 17035515›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2006

Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women.

John H Morrison, Roberta D Brinton, Peter J Schmidt, Andrea C Gore

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Differential effects of hormone therapy formulations on Parkinson's disease risk: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  16. Women's midlife: the front line of Alzheimer prevention.The Journal of clinical investigation · 2026
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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John H MorrisonFishberg Department of Neuroscience, Kastor Neurobiology of Aging Laboratories, New York, New York 10029, USA. john.morrison@mssm.edu
Roberta D Brinton
Peter J Schmidt
Andrea C Gore

Funding

Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERTA EILEEN BRINTON · 2006 to 2026
$53.7M
The Nonhuman Primate CoreP01AG016765 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BAXTER, MARK G · 1999 to 2016
$26.1M
SEX STEROIDS AND SYNAPTIC PLASTICITY IN AGINGP01AG014751 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 1997 to 2006
$7.8M
Glutamate receptors in aging cortical circuitsR37AG006647 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORRISON, JOHN H · 2007 to 2015
$4.8M
GLUTAMATE receptors in aging cortical circuitsR01AG006647 · NIA · SCRIPPS CLINIC AND RESEARCH FOUNDATION · PI MORRISON, JOHN HENRY · 1987 to 2005
$2.2M
PSYCHOBIOLOGY AND TREATMENT OF PERIMENOPAUSAL MOOD DISORDERSZ01MH002537 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SCHMIDT, PETER J · 1990 to 2008
$1.7M
The Neuroregulatory Effects of Gonadal Steroids in HumansZ01MH002874 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SCHMIDT, PETER · 2007 to 2008
$1.5M
Estrogen-Induced Neuroprotective Mitochondrial MechanismR01MH067159 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRINTON, ROBERTA DIAZ · 2003 to 2007
$1.3M
NIA NIH HHS AG026572NIA NIH HHS AG06647NIA NIH HHS AG14751NIA NIH HHS AG16765NIA NIH HHS P01 AG014751NIA NIH HHS P01 AG016765NIA NIH HHS P01 AG026572NIA NIH HHS R01 AG006647NIA NIH HHS R37 AG006647NIMH NIH HHS MH67159NIMH NIH HHS R01 MH067159
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsBrainEstrogensFemaleHormone Replacement TherapyHumansMenopauseNeurosciencesEstrogens

Identifiers

PMID17035515
PMCPMC6674699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.