ArticleBiological psychology2007
Respiratory sinus arrhythmia and diseases of aging: obesity, diabetes mellitus, and hypertension.
Article in Biological psychology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.
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- Exploring the Effects of a Brief Biofeedback Breathing Session Delivered Through the BioBase App in Facilitating Employee Stress Recovery: Randomized Experimental Study.JMIR mHealth and uHealth · 2020Trial
- Anxiety, depressive symptoms, and cardiac autonomic function in perimenopausal and postmenopausal women with hot flashes: a brief report.Menopause (New York, N.Y.) · 2018Trial
- The Physiological Component of the BOLD Signal: Impact of Age and Heart Rate Variability Biofeedback Training.bioRxiv : the preprint server for biology · 2025Article
- Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study.Journal of neurodevelopmental disorders · 2025Article
- The physiological component of the BOLD signal: Impact of age and heart rate variability biofeedback training.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Childhood Family Stress and Women's Health: Parasympathetic Activity as a Risk and Resiliency Factor.Applied psychophysiology and biofeedback · 2024Article
- Autonomic brain functioning and age-related health concerns.Current research in physiology · 2024Review
- Using spectral continuity to extract breathing rate from heart rate and its applications in sleep physiology.Frontiers in physiology · 2024Article
- Article
- Development and Parasympathetic Regulation in Male and Female Adolescents with Autism Spectrum Disorder: A Two-Timepoint Longitudinal Study.Journal of autism and developmental disorders · 2023Article
- Diagnostic and Physical Effects in Parasympathetic Response to Social Evaluation in Youth With and Without Autism Spectrum Disorder.Journal of autism and developmental disorders · 2022Article
- The Relationship Between Sexual Activity and Heart Rate Variability in Menopausal Women.Anatolian journal of cardiology · 2022Article
- Negative mood induction effects on problem-solving task in women with eating disorders: a multi-method examination.Journal of eating disorders · 2022Article
- Heart rate variability and HbA1c predict plasma interleukin-6 response to psychosocial stress challenge in trauma-exposed women with type 2 diabetes.Brain, behavior, & immunity - health · 2022Article
- Respiratory variability of sinus node activation in humans: insights from ultra-high-density mapping.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Article
- Autonomic vulnerability to biased perception of social inclusion in borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2021Article
- Influences of adversity across the lifespan on respiratory sinus arrhythmia during pregnancy.Developmental psychobiology · 2021Article
- Resting Heartbeat Complexity Predicts All-Cause and Cardiorespiratory Mortality in Middle- to Older-Aged Adults From the UK Biobank.Journal of the American Heart Association · 2021Article
- The Importance of Biobehavioral Research to Examine the Physiological Effects of Racial and Ethnic Discrimination in the Latinx Population.Frontiers in public health · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Associations between respiratory sinus arrhythmia (RSA) and several chronic diseases, including obesity, diabetes mellitus, and hypertension, have been documented in recent years. Although most evidence suggests reduced RSA is the result of chronic disease rather than the cause, some studies have documented reduced RSA among at-risk individuals prior to disease onset. These results raise the possibility that decreased vagal tone may play a role in the pathogenesis of certain chronic diseases. Presented here is a brief overview of studies which examine the relationship between vagal tone, as measured by RSA and baroreflex gain, and diseases of aging, including obesity, diabetes mellitus, and hypertension. Mechanisms by which vagal tone may be related to disease processes are discussed. In addition, we present results from a population-based study of RSA and hypertension in older adults. Consistent with previous studies, we found an inverse relationship between RSA and age, cigarette use, and diabetes. In logistic regression models which control for age, cigarette use, and diabetes, we found RSA was a significant negative predictor of hypertension. We conclude that the relationship between RSA and hypertension is somewhat independent of the age-related decline in parasympathetic activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.