Evidence map›Paper›PMID 17032453›Full record

ArticleEnvironmental health : a global access science source2006

A preliminary study of mercury exposure and blood pressure in the Brazilian Amazon.

Myriam Fillion, Donna Mergler, Carlos José Sousa Passos, Fabrice Larribe, Mélanie Lemire, Jean Rémy Davée Guimarães

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 5 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 5 syntheses or guidelines pooled it, 177 citations in OpenAlex.

  1. Pooled it
  2. Maternal Mercury Exposure and Hypertensive Disorders of Pregnancy: A Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Pooled it
  3. Pooled it
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  5. Hair as a Biomarker of Long Term Mercury Exposure in Brazilian Amazon: A Systematic Review.International journal of environmental research and public health · 2018
    Pooled it
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  11. Contaminant Metals and Cardiovascular Health.Journal of cardiovascular development and disease · 2023
    Review
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Myriam FillionCentre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, Succ. Centre-Ville, Montréal, Québec H3C 3P8, Canada. fillion.myriam@courrier.uqam.ca
Donna Mergler
Carlos José Sousa Passos
Fabrice Larribe
Mélanie Lemire
Jean Rémy Davée Guimarães
Université du Québec à Montréal · CAUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFish is considered protective for coronary heart disease (CHD), but mercury (Hg) intake from fish may counterbalance beneficial effects. Although neurotoxic effects of methylmercury (MeHg) are well established, cardiovascular effects are still debated. The objective of the present study was to evaluate blood pressure in relation to Hg exposure and fish consumption among a non-indigenous fish-eating population in the Brazilian Amazon.

methodsThe study was conducted among 251 persons from six communities along the Tapajós River, a major tributary of the Amazon. Data was obtained for socio-demographic information, fish consumption, height and weight to determine body mass index (BMI), systolic and diastolic blood pressure, and Hg concentration in hair samples.

resultsResults showed that overall, systolic and diastolic blood pressure, were relatively low (mean: 113.9 mmHg +/- 14.6 and 73.7 mmHg +/- 11.0). Blood pressure was significantly associated with hair total Hg (H-Hg), age, BMI and gender. No association was observed between fish consumption and blood pressure, although there were significant inter-community differences. Logistic regression analyses showed that the Odds Ratio (OR) for elevated systolic blood pressure (> or = 130 mmHg) with H-Hg > or = 10 microg/g was 2.91 [1.26-7.28], taking into account age, BMI, smoking, gender and community.

conclusionThe findings of this preliminary study add further support for Hg cardiovascular toxicity.

Indexed as

Blood PressureEnvironmental ExposureFood ContaminationAdolescentAdultAgedAged, 80 and overAnimalsBrazilDietFemaleFishesHumansHypertensionMaleMercuryMercury

Identifiers

PMID17032453
PMCPMC1617089
OpenAlexW1785699085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.