ArticleGenetics2006
Selection, recombination and demographic history in Drosophila miranda.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 76 citations in OpenAlex.
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- Adaptive Evolution Patterns in the Pacific Oyster Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2019Article
- Population Genetics ofInsects · 2019Article
- Relationship Among Intron Length, Gene Expression, and Nucleotide Diversity in the Pacific Oyster Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2018Article
- Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex.BMC genomics · 2017Article
- Natural Selection Drives Rapid Functional Evolution of Young Drosophila Duplicate Genes.Molecular biology and evolution · 2017Article
- Article
- Genomic changes following the reversal of a Y chromosome to an autosome in Drosophila pseudoobscura.Evolution; international journal of organic evolution · 2017Article
- Molecular Population Genetics.Genetics · 2017Review
- Genomic signatures of population decline in the malaria mosquito Anopheles gambiae.Malaria journal · 2016Article
- Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila.Genome biology and evolution · 2015Article
- Extraordinary Genetic Diversity in a Wood Decay Mushroom.Molecular biology and evolution · 2015Article
- Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species.Evolution; international journal of organic evolution · 2015Article
- Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana.Molecular biology and evolution · 2014Article
- Molecular hyperdiversity defines populations of the nematode Caenorhabditis brenneri.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Molecular hyperdiversity and evolution in very large populations.Molecular ecology · 2013Article
- Inferences of demography and selection in an African population of Drosophila melanogaster.Genetics · 2013Article
- Signatures of balancing selection are maintained at disease resistance loci following mating system evolution and a population bottleneck in the genus Capsella.BMC evolutionary biology · 2012Article
- Article
- Heterogeneity in genetic diversity among non-coding loci fails to fit neutral coalescent models of population history.PloS one · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Selection, recombination, and the demographic history of a species can all have profound effects on genomewide patterns of variability. To assess the impact of these forces in the genome of Drosophila miranda, we examine polymorphism and divergence patterns at 62 loci scattered across the genome. In accordance with recent findings in D. melanogaster, we find that noncoding DNA generally evolves more slowly than synonymous sites, that the distribution of polymorphism frequencies in noncoding DNA is significantly skewed toward rare variants relative to synonymous sites, and that long introns evolve significantly slower than short introns or synonymous sites. These observations suggest that most noncoding DNA is functionally constrained and evolving under purifying selection. However, in contrast to findings in the D. melanogaster species group, we find little evidence of adaptive evolution acting on either coding or noncoding sequences in D. miranda. Levels of linkage disequilibrium (LD) in D. miranda are comparable to those observed in D. melanogaster, but vary considerably among chromosomes. These patterns suggest a significantly lower rate of recombination on autosomes, possibly due to the presence of polymorphic autosomal inversions and/or differences in chromosome sizes. All chromosomes show significant departures from the standard neutral model, including too much heterogeneity in synonymous site polymorphism relative to divergence among loci and a general excess of rare synonymous polymorphisms. These departures from neutral equilibrium expectations are discussed in the context of nonequilibrium models of demography and selection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.