ArticleGenetics2006
Evolution of amino-acid sequences and codon usage on the Drosophila miranda neo-sex chromosomes.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 54 citations in OpenAlex.
- HJ Muller and the Relationship Between Sex Chromosome Degeneration and the Evolution of Dosage Compensation.Genome biology and evolution · 2025Review
- Characterization of the transposable element landscape shaping the Ectocarpus genome.Genome biology · 2025Article
- A model of Hill-Robertson interference caused by purifying selection in a nonrecombining genome.Genetics · 2025Article
- Can a Y Chromosome Degenerate in an Evolutionary Instant? A Commentary on Fong et al. 2023.Genome biology and evolution · 2023Article
- Tempo of Degeneration Across Independently Evolved Nonrecombining Regions.Molecular biology and evolution · 2022Article
- PromethION Sequencing and Assembly of the Genome of Micropoecilia picta, a Fish with a Highly Degenerated Y Chromosome.Genome biology and evolution · 2021Article
- Evolution of recombination rates between sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- The fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SB.Molecular ecology · 2017Article
- Article
- Degeneration of the nonrecombining regions in the mating-type chromosomes of the anther-smut fungi.Molecular biology and evolution · 2015Article
- Positive and purifying selection on the Drosophila Y chromosome.Molecular biology and evolution · 2014Article
- Genetic diversity in the interference selection limit.PLoS genetics · 2014Article
- Y-chromosome evolution: emerging insights into processes of Y-chromosome degeneration.Nature reviews. Genetics · 2013Review
- Molecular evolution in nonrecombining regions of the Drosophila melanogaster genome.Genome biology and evolution · 2012Article
- Review
- Why chromosome palindromes?International journal of evolutionary biology · 2012Article
- Nonrandom gene loss from the Drosophila miranda neo-Y chromosome.Genome biology and evolution · 2011Article
- Estimating the parameters of selection on nonsynonymous mutations in Drosophila pseudoobscura and D. miranda.Genetics · 2010Article
- Article
- Evolution of sex chromosomes in insects.Annual review of genetics · 2010Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have studied patterns of DNA sequence variation and evolution for 22 genes located on the neo-X and neo-Y chromosomes of Drosophila miranda. As found previously, nucleotide site diversity is greatly reduced on the neo-Y chromosome, with a severely distorted frequency spectrum. There is also an accelerated rate of amino-acid sequence evolution on the neo-Y chromosome. Comparisons of nonsynonymous and silent variation and divergence suggest that amino-acid sequences on the neo-X chromosome are subject to purifying selection, whereas this is much weaker on the neo-Y. The same applies to synonymous variants affecting codon usage. There is also an indication of a recent relaxation of selection on synonymous mutations for genes on other chromosomes. Genes that are weakly expressed on the neo-Y chromosome appear to have a faster rate of accumulation of both nonsynonymous and unpreferred synonymous mutations than genes with high levels of expression, although the rate of accumulation when both types of mutation are pooled is higher for the neo-Y chromosome than for the neo-X chromosome even for highly expressed genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.